Dendrimeric Organochalcogenides as Catalysts for the Activation of Hydrogen Peroxide

树枝状有机硫族化物作为过氧化氢活化催化剂

• 批准号: 0108521
• 负责人: Michael Detty
• 金额: $ 22.8万
• 依托单位: SUNY at Buffalo
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-07-01 至 2004-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0108521&HistoricalAwards=false
• 关键词: Dendrimeric; Organochalcogenides; Catalysts; Activation; Hydrogen

Professor Michael R. Detty in the Department of Chemistry at the State University of New York at Buffalo is supported by the Organic and Macromolecular Chemistry Program for his studies incorporating organoselenides and tellurides into dendrimers. In the presence of hydrogen peroxide, these compounds may function as mild oxidants. These dendrimeric catalysts show potential as environmentally friendly oxidizing agents since the use of heavy metal oxidants and elemental halogens can be replaced by hydrogen peroxide.With the support of the Organic and Macromolecular Program, Professor Detty is developing catalysts which are mimics of halo- and thiolperoxidases, enzymes which catalyze the oxidation of halide salts and thiols, respectively. These catalysts avoid the use of poisonous reagents and therefore are potentially valuable as environmentally benign alternatives to heavy metal oxidants or elemental halogens.

Michael R.位于布法罗的纽约州立大学化学系的Detty因其将有机硒化物和碲化物纳入树枝状聚合物的研究而得到有机和大分子化学计划的支持。 在过氧化氢的存在下，这些化合物可以作为温和的氧化剂。 这些树枝状聚合物催化剂显示出作为环境友好型氧化剂的潜力，因为使用的重金属氧化剂和元素卤素可以被过氧化氢代替。在有机和大分子计划的支持下，Detty教授正在开发催化剂，它们是卤代和硫代过氧化物酶的模拟物，分别催化卤化物盐和硫醇的氧化。 这些催化剂避免了有毒试剂的使用，因此作为重金属氧化剂或元素卤素的环境友好的替代品是潜在有价值的。