Dendrimeric Organochalcogenides as Catalysts for the Activation of Hydrogen Peroxide

纽约州立大学布法罗分校化学系的Michael R.Detty教授因其将有机硒和碲化物引入树枝状大分子的研究而得到有机和高分子化学计划的支持。在过氧化氢存在下，这些化合物可以起到温和的氧化剂的作用。由于使用重金属氧化剂和元素卤素可以被过氧化氢取代，这些树状大分子催化剂显示出作为环境友好氧化剂的潜力。在有机和大分子计划的支持下，戴蒂教授正在开发模拟卤代和硫代过氧化物酶的催化剂，这两种酶分别催化卤化物盐和硫醇的氧化。这些催化剂避免使用有毒试剂，因此作为重金属氧化剂或元素卤素的环境友好替代品具有潜在的价值。

Professor Michael R. Detty in the Department of Chemistry at the State University of New York at Buffalo is supported by the Organic and Macromolecular Chemistry Program for his studies incorporating organoselenides and tellurides into dendrimers. In the presence of hydrogen peroxide, these compounds may function as mild oxidants. These dendrimeric catalysts show potential as environmentally friendly oxidizing agents since the use of heavy metal oxidants and elemental halogens can be replaced by hydrogen peroxide.With the support of the Organic and Macromolecular Program, Professor Detty is developing catalysts which are mimics of halo- and thiolperoxidases, enzymes which catalyze the oxidation of halide salts and thiols, respectively. These catalysts avoid the use of poisonous reagents and therefore are potentially valuable as environmentally benign alternatives to heavy metal oxidants or elemental halogens.