SGER: Controlled Self-Assembly of a Nanotriangle

摘要：塔夫茨大学的edward Goldberg提出了通过控制自组装来构建纳米结构的方法：它们将由单位蛋白质棒（大约50nm长的棒）组成，这些蛋白质棒将以等边三角形的形状组织，其侧面将由互补的结合对组成。这些三角形的组装将在第三维度中按所需的顺序和增长阶段进行。以这种方式，“自下而上”的纳米阵列平行制造将成为一种实际的可能性。使用三个绑定对的顺序组装。有三个主要的挑战：解决相关的结合对；将它们定位在适当的间距，并确定每个新的所需纳米结构的分期程序。这些任务的复杂性，对于任何真正理想的纳米结构组装，都需要大量的步骤（设计和生产模块化单元棒，将其中一个棒与矩阵相关联，并在可编程的三角形生成中组装单元棒）。

AbstractCTS-0124784Edward Goldberg, Tufts UniversityIt is proposed to build nanostructures by controlled self-assembly: they would be made of unit protein rods (approximately 50nm long rods) which would be organized in the shape of equilateral triangles, the sides of which would be made of complimentary binding pairs. Assembly of these triangles will be carried out by stages in a third dimension, with the desired order and growth. In this manner, the "bottom up" parallel manufacture of nanoarrays will become a practical possibility. A sequential assembly of three binding pairs is used. There are three major challenges: addressing the relevant binding pairs; positioning them in proper spacing and identifying the staging procedure for each new desired nanostructure. The complexity of these tasks, for any truly desirable assembly of nanostructures, demands a large number of steps (design and produce modular unit rods, associate one of the rods to a matrix and assemble the unit rods in a programmatic generation of triangles).