Purchase of a Circular Dichroic Spectrophotometer for Research and Teaching

购买圆二色分光光度计用于研究和教学

• 批准号: 0130787
• 负责人: Stanley Radel
• 金额: --
• 依托单位: CUNY City College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-02-01 至 2005-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0130787&HistoricalAwards=false
• 关键词: Purchase; Circular; Dichroic; Spectrophotometer; Research

With support from the Chemistry Research Instrumentation and Facilities (CRIF) Program, the Department of Chemistry at CUNY City College will acquire a Circular Dichroism Spectrometer. This equipment will enhance research in a number of areas including a) studies on DNA oligomers and duplexes; b) investigations on the characterization of isolated fragments of variants of Trx as a proxy for the unfolded state of the protein under non-denaturing conditions; and c) development of biomaterials for nanoscale photonic applications. Circular dichroism spectroscopy is an extremely useful tool in modern analytical chemistry. It provides a very reliable and sensitive method for assigning absolute molecular configurations. The results from these studies will have an impact in a number of areas including materials chemistry and biochemistry.

在化学研究仪器和设施（CRIF）计划的支持下，纽约市立大学化学系将获得一台圆二色光谱仪。这一设备将加强若干领域的研究，包括a）对DNA寡聚体和双链体的研究; B）对Trx变体的分离片段的特性进行研究，作为非变性条件下蛋白质未折叠状态的代表; c）开发用于纳米级光子应用的生物材料。 圆二色谱是现代分析化学中一种非常有用的工具。 它提供了一个非常可靠和灵敏的方法来指定绝对分子构型。 这些研究的结果将在许多领域产生影响，包括材料化学和生物化学。