Biophotonics: Dual-FRET Molecular Beacons for Early Cancer Detection
Biophotonics: Dual-FRET Molecular Beacons for Early Cancer Detection
批准号:
0222211
负责人:
Gang Bao
金额:
$29.6万
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
2002
资助国家:
美国
项目状态:
已结题
起止时间:
2002-08-01 至 2006-07-31
中文摘要
点击翻译按钮获取中文摘要
英文摘要
0222211BaoThe applicants propose to develop a novel dual-FRET molecular beacons methodology for the detection of cancer cells with high specificity, sensitivity and efficiency. Molecular beacons (MBs) are single-stranded oligonucleotides with a stem-loop hairpin structure and dual-labeled with a fluorophore at one end and a quencher at the other. Delivering MBs into cells will result in a fluorescence signal if the MBs hybridize to target mRNAs. Thus, when the target mRNAs correspond to the molecular markers of a cancer, cancer cells (bright) can be distinguished from normal cells (dark ).
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会议论文
Workshop on Engineering Innovation for Health; Houston, Texas; 2024
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批准号:2333270
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项目类别:Standard Grant
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资助金额:$1.0万
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财政年份:2023
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负责人:Gang Bao
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依托单位:
ASME 2016 Nanoengineering for Medicine and Biology Conference Houston, TX, Feb 21-24, 2016
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批准号:1606794
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项目类别:Standard Grant
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资助金额:$2.5万
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财政年份:2016
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负责人:Gang Bao
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依托单位:
Workshop on Frontiers in Bioengineering Research, February 25-26, 2013, Atlanta, GA
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批准号:1258463
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项目类别:Standard Grant
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资助金额:$2.5万
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财政年份:2012
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负责人:Gang Bao
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依托单位:
Modeling, Analysis, and Computation of Diffractive and Nano Optics
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批准号:0908325
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项目类别:Standard Grant
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资助金额:$34.19万
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财政年份:2009
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负责人:Gang Bao
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依托单位:
Gaussian Beam Methods for Large-Scale Computational Electromagnetics and Applications
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批准号:0830161
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项目类别:Standard Grant
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资助金额:$25.0万
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财政年份:2008
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负责人:Gang Bao
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依托单位:
Workshop on Cell and Molecular Biomechanics
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批准号:0834046
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项目类别:Standard Grant
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资助金额:$2.5万
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财政年份:2008
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负责人:Gang Bao
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依托单位:
Collaborative Research: CMG --Quantifying Tectonic and Geomorphic Interpretations of Thermochronometer Data with Inverse Problem Theory
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批准号:0724527
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项目类别:Standard Grant
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资助金额:$21.72万
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财政年份:2007
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负责人:Gang Bao
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依托单位:
Direct and Inverse Modeling of Diffractive Optics and Near-Field Optics
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批准号:0604790
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项目类别:Standard Grant
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资助金额:$0.0万
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财政年份:2006
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负责人:Gang Bao
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依托单位:
Conference Support for 2006 MRS Symposium: Nanostructured Probes for Molecular Bioimaging
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批准号:0621295
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项目类别:Standard Grant
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资助金额:$1.0万
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财政年份:2006
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负责人:Gang Bao
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依托单位:
Collaborative Research: Foundations of Solving Large Direct and Inverse Scattering Problems - Algorithm Analysis and System Support
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批准号:0514078
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项目类别:Standard Grant
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资助金额:$0.0万
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财政年份:2005
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负责人:Gang Bao
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依托单位:
Conference Support for 2003 ASME Symposium: Mechanics of Biological Materials; November 16-21, 2003; Washington, DC
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批准号:0345373
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项目类别:Standard Grant
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资助金额:$0.5万
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财政年份:2003
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负责人:Gang Bao
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依托单位:
Direct and Inverse Problems in Diffractive Optics Modeling
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批准号:0104001
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项目类别:Continuing Grant
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资助金额:$32.0万
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财政年份:2001
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负责人:Gang Bao
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依托单位:
Modeling of Micro-Optics and Electromagnetics
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批准号:9972292
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项目类别:Standard Grant
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资助金额:$0.0万
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财政年份:1999
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负责人:Gang Bao
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依托单位:
Modeling of Micro-Optics and Electromagnetics
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批准号:0096046
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项目类别:Standard Grant
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资助金额:$4.62万
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财政年份:1999
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负责人:Gang Bao
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依托单位:
U.S.-France Cooperative Research: Modeling and Optimal Design in Micro-Optics
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批准号:9996446
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项目类别:Standard Grant
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资助金额:$1.56万
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财政年份:1999
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负责人:Gang Bao
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依托单位:
U.S.-France Cooperative Research: Modeling and Optimal Design in Micro-Optics
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批准号:9815798
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项目类别:Standard Grant
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资助金额:$0.15万
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财政年份:1999
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负责人:Gang Bao
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依托单位:
Modeling and Design of Diffractive Optics
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批准号:9996439
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项目类别:Standard Grant
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资助金额:$1.34万
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财政年份:1999
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负责人:Gang Bao
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依托单位:
Inverse Diffraction Problems in Optics
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批准号:9996416
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项目类别:Standard Grant
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资助金额:$4.4万
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财政年份:1999
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负责人:Gang Bao
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依托单位:
Inverse Diffraction Problems in Optics
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批准号:9803604
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项目类别:Standard Grant
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资助金额:$7.92万
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财政年份:1998
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负责人:Gang Bao
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依托单位:
Modeling and Design of Diffractive Optics
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批准号:9803809
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项目类别:Standard Grant
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资助金额:$0.0万
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财政年份:1998
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负责人:Gang Bao
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依托单位:
国内基金
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