SBIR Phase I: Purification of Metallic Nitride Nanomaterials by Chemical Separation

SBIR 第一阶段：通过化学分离纯化金属氮化物纳米材料

• 批准号: 0232204
• 负责人: Steven Stevenson
• 金额: $ 10万
• 依托单位: Luna Innovations, Incorporated
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-01-01 至 2003-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0232204&HistoricalAwards=false
• 关键词: SBIR; Phase; Purification; Metallic; Nitride

This Small Business Innovative Research (SBIR) Phase I project will develop trimetallic-nitride-template metallofullerenes (trimetaspheres) for use as improved MRI contrast agents. The largest barrier to providing these trimetasphere materials in significant quantities is the lack of an economical, efficient means of separating these materials from undesirable empty-cage C60 and C70 fullerenes. To address this issue, the proposed effort offers innovative, ingenious solutions to the problem of large-scale synthesis and separation processes for these nanomaterials. The project tasks are 1) to increase generator throughput of trimetasphere-containing soot, 2) to advance vapor-phase deposition techniques as a prepurification step, and 3) to establish the feasibility of a chemical-separation process, which will enable large-scale nanomaterials production. The expectation is to totally remove HPLC from all stages of purification. Commercially, trimetaspheres are expected to find valuable applications in 1) improved medical care through novel imaging and diagnostic properties, 2) new pharmaceuticals, via high throughput screening, 3) faster and more productive internet use, through faster optical switches and components that provide higher bandwidth, 4) faster computers, through quantum computing devices built from nanomaterials, and 5) military devices including sensors, imaging devices, non-linear optical devices, new superconductors and variable capacitors.

这个小企业创新研究（SBIR）第一阶段项目将开发三金属氮化物模板金属富勒烯（trimetaspheres），用作改进的MRI造影剂。大量提供这些三元球材料的最大障碍是缺乏将这些材料与不期望的空笼C60和C70富勒烯分离的经济、有效的手段。 为了解决这个问题，拟议的努力提供了创新的，巧妙的解决方案，这些纳米材料的大规模合成和分离过程的问题。该项目的任务是：1）增加含trimetpheres烟灰的发生器吞吐量，2）推进气相沉积技术作为预净化步骤，3）建立化学分离过程的可行性，这将使大规模纳米材料生产成为可能。 预期从所有纯化阶段完全去除HPLC。 在商业上，三元球有望在以下方面找到有价值的应用：1）通过新的成像和诊断特性改善医疗保健，2）通过高通量筛选开发新药物，3）通过更快的光开关和提供更高带宽的组件更快和更有生产力的互联网使用，4）通过由纳米材料构建的量子计算设备，5）军用器件，包括传感器、成像器件、非线性光学器件、新型超导体和可变电容器。