Dissertation Enhancement Award (Germany) International: Scanning Electrochemical Microscopy for Ultra-Sensitive Electrochemical Immunoassay

0233810Heinman本学位论文增强奖支持辛辛那提大学威廉·海尼曼实验室的一名研究生在德国奥尔登堡大学化学系冈瑟·维特斯托克的实验室工作两个月。这项研究的目标是发展一种超灵敏和微型化的免疫分析方法，适用于临床诊断和生物制剂的检测。这一目标将通过使用扫描电化学显微镜来执行和检测免疫分析来实现。使用微珠作为免疫分析的流动固相增加了表面积与体积的比率，因为它们可以在没有溶液的情况下分散，从而最大限度地减少了扩散距离。这项研究可能导致高密度芯片测试系统的新技术，并可能在毒素、细菌、孢子和病毒等生物制剂的检测中受益。该项目也有明确的教育目标。该项目将允许研究生从在另一个国家进行研究中受益。她将在学习重要的新技术技能的同时，提高对世界的鉴赏力。

0233810HeinemanThis dissertation enhancement award supports a graduate student from William Heineman's lab at the University of Cincinnati during here two-month tenure in the lab of Gunther Wittstock in the Department of Chemistry at the University of Oldenburg, Germany. The goal of the research is to develop an ultrasensitive and miniaturized immunoassy applicable to clinical diagnostics and detection of biowarfare agents. The goal will be met using scanning electrochemical microscopy in to perform and detect the immunoassay. Using microbeads as a mobile solid phase for immounoassay increases the surface area to volume ratio, since they can be dispersed without solution, which minimizes diffusion distances. This research could lead to new technologies for high-density chip-based testing systems and could benefit in the detection of biowarfare agents such as toxins, bacteria, spores, and viruses.The project also has a clear educational objective. The project will allow a graduate student to benefit from performing research in another country. She will develop a heightened appreciation of the world while also learning important new technical skills.