Inter-American Materials Collaboration: Mexico/United States

美洲材料合作：墨西哥/美国

• 批准号: 0303539
• 负责人: Curtis Frank
• 金额: --
• 依托单位: Stanford University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-08-01 至 2009-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0303539&HistoricalAwards=false
• 关键词: Inter; American; Materials; Collaboration; Mexico

This Inter-American Materials Collaboration brings together groups led by Curtis Frank, Stanford University, and Craig Hawker, IBM-Almaden, at the Center for Polymer Interfaces and Macromolecular Assemblies (CPIMA) in the US, and A. Licea-Claverie, Instituto Tecnologico de Tijuana (ITT), and J. Cornejo-Bravo, Universidad Autonoma de Baja California (BAJA), in Mexico. The project aims to develop new synthetic approaches and characterization techniques for the preparation and study of well-defined smart materials. Living free radical polymerization techniques are developed as a platform for the synthesis of polymers with controlled structure and architecture that respond to two different stimuli: temperature and pH. Structural features, such as the separation of the responsive units via the formation of block copolymers, and the nature of the chain architectures (linear, grafted, stars, and networks) are explored in detail. Furthermore, the reversible temperature- or pH-driven formation of supramolecular structures in solution from the linear, grafted, and star architectures are studied. A more fundamental challenge is to understand the relationships among structure, property, and function for these stimuli-responsive materials. Based on this understanding, the controlled release of drugs and other small molecules from gels, stars, polymer-drug complexes, or supramolecular structures (e.g. polymeric micelles) is examined. A vigorous and interdisciplinary teaching and outreach program is a critical feature of this project and significantly extends the collaborative relationships built on these scientific foundations. Educational and teaching expertise in polymer chemistry and materials research that has been developed in CPIMA is transferred to both ITT and BAJA, while the exposure of undergraduates, graduates, and post-doctoral scholars to research at all three institutions establishes a unique collaborative environment. In addition, exposure of undergraduates and graduates to a combined international academic-academic and industrial-academic setting provides an invigorating research experience. This award is supported by the Division of Materials Research, the Office of International Science and Engineering, and the Office of Multidisciplinary Activities in the Directorate for Mathematical and Physical Sciences.

这个美洲材料合作组织汇集了由斯坦福大学的Curtis Frank和IBM Almaden的克雷格霍克领导的美国聚合物界面和大分子组装中心（CPIMA）的小组，以及A。Licea-Claverie，Instituto Tecnologico de Tianjin（ITT）和J. Cornejo-Bravo，Universidad Autonoma de下加利福尼亚（BAJA），墨西哥。该项目旨在开发新的合成方法和表征技术，用于制备和研究定义明确的智能材料。 活性自由基聚合技术的发展作为一个平台，用于合成聚合物的控制结构和架构，响应于两种不同的刺激：温度和pH值。结构特征，如通过形成嵌段共聚物的响应单元的分离，和链架构的性质（线性，接枝，星，和网络）进行了详细探讨。 此外，可逆的温度或pH值驱动的超分子结构的形成在溶液中的线性，接枝，和星星架构进行了研究。 一个更根本的挑战是了解这些刺激响应材料的结构，性质和功能之间的关系。 基于这种理解，药物和其他小分子从凝胶，星，聚合物-药物复合物，或超分子结构（如聚合物胶束）的控制释放进行检查。 一个充满活力的跨学科教学和推广计划是该项目的一个重要特征，并显着扩展了建立在这些科学基础上的合作关系。 在CPIMA开发的高分子化学和材料研究的教育和教学专业知识被转移到ITT和BAJA，而本科生，研究生和博士后学者在所有三个机构的研究建立了一个独特的合作环境。此外，本科生和研究生接触到一个结合国际学术和工业学术环境提供了一个令人振奋的研究经验。该奖项由材料研究部，国际科学与工程办公室以及数学和物理科学局多学科活动办公室支持。