Phase Separation Kinetics of Polyelectrolyte Solutions

聚电解质溶液的相分离动力学

• 批准号: 0318574
• 负责人: Murugappan Muthukumar
• 金额: $ 31.2万
• 依托单位: University of Massachusetts Amherst
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-07-01 至 2006-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0318574&HistoricalAwards=false
• 关键词: Phase; Separation; Kinetics; Polyelectrolyte; Solutions

Clustering of charged macromolecules in aqueous solutions and their thermodynamic stability are of central importance in all forms of life. Polyelectrolyte solutions in water exhibit complex behavior and present many intellectual challenges. Experiments using light scattering and neutron scattering, and theoretical and modeling investigations of polyelectrolyte phase behavior are proposed. The proposal contains two major challenges. In the first, the molecular origins of the nature and extent of clustering among similarly charged polyelectrolytes mediated by divalent counterions will be explored. In the second, the kinetics of phase separation in polyelectrolyte solutions will be measured and understood. The specific experimental system of the proposed research is aqueous solutions of sodium polystyrene sulfonate containing known amounts of barium chloride. The results of the proposed work will provide a fundamental understanding of polyelectrolyte phase behavior.The proposed research will have impact in medical research on disease control and a number of key industries including food, cosmetics, personal care products, and pharmaceuticals. Furthermore, polyelectrolytes are emerging to be the most important, and least understood, materials. Training of graduate students in this important research area is the strong educational component of the proposed activity.

带电大分子在水溶液中的聚集及其热力学稳定性在所有形式的生命中都是至关重要的。 聚电解质水溶液表现出复杂的行为，并提出了许多智力挑战。 利用光散射和中子散射的实验，和理论和模拟研究的双相行为提出。 该提案包含两大挑战。 在第一，分子起源的性质和程度之间的类似的带电聚电解质介导的二价抗衡离子的集群将进行探索。 在第二部分中，将测量和理解在水溶液中相分离的动力学。 具体的实验系统的拟议研究是聚苯乙烯磺酸钠的水溶液中含有已知量的氯化钡。 这项研究的结果将为人类对相变行为的理解提供基础，并将对疾病控制的医学研究以及食品、化妆品、个人护理产品和制药等关键行业产生影响。 此外，聚电解质正在成为最重要但最不为人所知的材料。 在这一重要研究领域培养研究生是拟议活动的重要教育组成部分。