SBIR Phase I: Low Cost, Needleless Drug Injection System

SBIR 第一阶段：低成本、无针药物注射系统

• 批准号: 0319295
• 负责人: James Scherer
• 金额: $ 10万
• 依托单位: NOVAWAVE TECHNOLOGIES
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-07-01 至 2004-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0319295&HistoricalAwards=false
• 关键词: SBIR; Phase; Low; Cost; Needleless

This Small Business Innovation Research (SBIR) Phase I project will demonstrate the feasibility of producing a novel, needleless drug injection system for widespread vaccination applications. The key element in the technology will be a novel high pressure pumping device. This device will enable high pressure flows to be precisely and easily controlled by the user in order to control injection drug amount. This is a capability currently lacking in existing low cost needleless injector technology. The Phase I project will show that the high pressure pumping device actually works. The follow on Phase II effort will focus on building a prototype system that will integrate the pump with the control electronics and injection nozzle for subsequent testing. The commercial application of this project is in the area of drug delivery. The proposed needleless injection device is expected to be reused thousands of times with a single low voltage battery source and will be invaluable for widespread vaccination use in the field for domestic as well as foreign markets. The unique ability to precisely meter injection volume will enable the device to be easily adjusted in the field to deliver a dosage appropriate for the associated weight, age, or physical condition of the patient.

这个小型企业创新研究(SBIR)第一阶段项目将展示生产一种新的无针药物注射系统的可行性，用于广泛的疫苗接种应用。这项技术的关键是一种新型的高压泵送装置。该装置将使用户能够精确和容易地控制高压流量，以控制注射药量。这是目前现有的低成本无针注射器技术所缺乏的能力。一期工程将展示高压抽水装置实际工作。第二阶段的后续工作将集中在建立一个原型系统，该系统将把泵与控制电子设备和喷嘴集成在一起，以供后续测试。该项目的商业应用是在药物输送领域。拟议的无针注射装置预计将在单一低压电池源的情况下重复使用数千次，对于在国内外市场广泛使用疫苗具有无价的价值。独特的精确测量注射量的能力将使该设备能够在现场轻松调整，以提供适合患者相关体重、年龄或身体状况的剂量。