Understanding biological nitrogen fixation: an investigation of multi-electron reduction catalysis at novel iron-sulfur clusters

了解生物固氮：新型铁硫簇的多电子还原催化研究

• 批准号: DP0988410
• 负责人: A/Prof Stephen Colbran
• 金额: $ 22.15万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2012-06-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0988410
• 关键词: Understanding; biological; nitrogen; fixation; investigation

A new class of iron-sulfur clusters held together by a central light atom will be prepared and their reactions thoroughly studied. These clusters are important because they will have the same structure as the iron-molybdenum cluster of the enzyme nitrogenase. This enzyme fixes atmospheric nitrogen as ammonia. It is the primary route of nitrogen entry into all living systems. Industrially ammonia is produced in an energy-demanding process on a vast scale. The studies will provide insights into how nitrogenase works and how to design new multi-electron reduction catalysts. The research may lead to new energy-efficient routes to ammonia and to other new alternative fuel sources. Such processes would transform Australian industry and how we live.

我们将制备一类由中心轻原子连接的新型铁硫簇合物，并深入研究它们的反应。这些簇是重要的，因为它们将具有与固氮酶的铁钼簇相同的结构。这种酶将大气中的氮转化为氨。它是氮进入所有生命系统的主要途径。在工业上，氨的生产是一个大规模的能源需求过程。这些研究将为固氮酶如何工作以及如何设计新的多电子还原催化剂提供见解。这项研究可能会导致新的能源效率的路线，氨和其他新的替代燃料来源。这些过程将改变澳大利亚的工业和我们的生活方式。