RUI: Time-Dependent Electroosmotic Flow Studies in Coated Capillaries

RUI：涂层毛细管中随时间变化的电渗流研究

• 批准号: 0400964
• 负责人: Kimberley Frederick
• 金额: --
• 依托单位: College of the Holy Cross
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-05 至 2009-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0400964&HistoricalAwards=false
• 关键词: RUI; Time; Dependent; Electroosmotic; Flow

Professor Kimberly Schrum of Whittier College is supported by the Analytical and Surface Chemistry Program with a RUI grant focused on electroosmotic flow (EOF). The goals are to improve the understanding of EOF in fused silica capillaries, evaluate and characterize new coating materials, and study the relationship between surface morphology and EOF for polyelectrolyte multilayers. Photobleaching zone migration (PBZM) will be used to reach the objectives. An instrument for PBZM measurements will be improved by developing a 'palette' of neutral marker dyes for flow measurements. The second phase of the activity will enable predictions of changes in EOF as solvent/solute changes take place. The group will also study rapid assessment of coating processes and examine the relationship between surface morphology and EOF in polyelectrolyte multilayer systems.The proposed activity represents a fundamental contribution to the fields of separation science, nanotechnology and materials science and also provides undergraduate students with a unique interdisciplinary opportunity. EOF is relied on in many of the emerging miniaturization technologies. In addition, the results of the activity will be of use to the biomedical research community.

惠蒂尔学院的 Kimberly Schrum 教授得到了分析和表面化学项目的支持，并获得了专注于电渗流 (EOF) 的 RUI 资助。 目标是提高对熔融石英毛细管中 EOF 的理解，评估和表征新型涂层材料，并研究聚电解质多层的表面形态与 EOF 之间的关系。 将使用光漂白区迁移（PBZM）来实现目标。通过开发用于流量测量的中性标记染料“调色板”，将改进 PBZM 测量仪器。该活动的第二阶段将能够预测溶剂/溶质发生变化时 EOF 的变化。该小组还将研究涂层工艺的快速评估，并研究聚电解质多层系统中表面形态与EOF之间的关系。所提出的活动代表了对分离科学、纳米技术和材料科学领域的根本性贡献，也为本科生提供了独特的跨学科机会。 许多新兴的小型化技术都依赖于 EOF。 此外，该活动的结果将对生物医学研究界有用。