Collaborative Research: RUI-Studies of Antigen/Antibody Interactions with Nanoparticles

美世大学的Caryn Seney教授和Fort Valley State College的Robin Bright教授得到了分析和表面化学计划的支持，以优化使用混合的银和金纳米颗粒的抗体/抗原相互作用的表面增强拉曼光谱(SERS)信号。新的想法是使用金纳米颗粒固定蛋白质，而不会导致银纳米颗粒有时导致的结构退化，而随后的银的加入提供了SERS信号的增强。该项目将佐治亚州相隔30英里的两所本科院校连接起来，其中一所(FVSC)是HBCU。本科生，包括一些来自代表不足的群体的学生，正在被介绍及时地结合纳米材料、光谱学、免疫化学和生物分析检测。该项目为生物传感器的发展提供了基础背景。

Professors Caryn Seney of Mercer University and Robin Bright of Fort Valley State College are supported by the Analytical and Surface Chemistry Program to optimize surface enhanced Raman spectroscopy (SERS) signals from antibody/antigen interactions using mixed silver and gold nanoparticles. The new idea is to use gold nanoparticles to immobilize proteins without the structural degradation sometimes induced by silver nanoparticles, while the subsequent addition of silver provides enhancement of the SERS signal. This project links two undergraduate institutions in Georgia, separated by 30 miles, one (FVSC), an HBCU. Undergraduate students, including some from underrepresented groups, are being introduced to a timely combination of nanomaterials, spectroscopy, immunochemistry and bioanalyte detection. The project provides fundamental background for biosensor development.