Increasing Breadth in the Separation Science Curriculum in Chemistry: Addition of HPLC and CE to Analytical, Organic, and Biochemistry Lab Instruction

化学（12）为了让学生了解高效液相色谱（HPLC）和毛细管电泳（CE）的能力和局限性，我们正在开发新的和适合的分离实验。该项目涉及多个化学实验室的分离科学实验和概念，以便通过反复接触，学生对影响分离的实验参数有更清晰的了解。学生将以约翰·沃尔特斯（John Walters）在一系列文章（Walters, j.p.; analyst）中描述的小组形式进行合作。化学，1991,63,971A；分析化学。化学，1991,63,1077A；分析化学。化学，1991,63,1179A)。最终，学生学会调整这些参数来改善分离。他们还通过分析具有不同目标的广泛样品来学习这些仪器技术的全方位适用性，包括手性分析，方法开发和模拟，以及蛋白质和肽表征。化学专业的学生会发现，分离科学在所有分子科学中都有明显的适用性，他们会变得更有适应能力，用比以前更完整和统一的方法来解决化学问题。

Chemistry (12)New and adapted separation experiments are being developed to build awareness among our students of the capabilities and limitations of high performance liquid chromatography (HPLC) and capillary electrophoresis (CE). The project involves incorporating separation science experiments and concepts across several chemistry laboratories so that, with repeated exposure, students have a clearer understanding of the experimental parameters that affect separation. Students will work together in an adaptation of the group format described by John Walters in a series of articles (Walters, J. P.; Analyt. Chem. 1991, 63, 971A; Analyt. Chem. 1991, 63, 1077A; Analyt. Chem. 1991, 63, 1179A). Ultimately students learn to adjust these parameters to improve separation. They also learn the full range of applicability of these instrumental techniques by analyzing a broad range of samples with different goals in mind, including chiral analysis, methods development and simulation, and protein and peptide characterization. Chemistry majors will discover that separation science has obvious applicability across all of the molecular sciences, and they will become more adaptable in their ability to solve chemical problems with a more complete and unified approach than before.