STTR Phase I: Production and Characterization of Recombinant Gelatin in Transgenic Rice Cell Cultures

STTR 第一阶段：转基因水稻细胞培养物中重组明胶的生产和表征

• 批准号: 0419707
• 负责人: Julio Baez
• 金额: $ 10万
• 依托单位: FibroGen, Inc.
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-07-01 至 2005-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0419707&HistoricalAwards=false
• 关键词: STTR; Phase; Production; Characterization; Recombinant

This Small Technology Transfer Research (STTR) Phase I project will evaluate a rice cell culture system for the production of recombinant gelatin (rGelatin) designed for improved capsule performance. The commercial application of this project will be on capsule manufacturers serving the pharmaceutical industry. Plant systems used to create rGelatin will offer a lower cost production system compared to other recombinant platforms. Such a recombinant product will be safer than animal-derived gelatin and more acceptable to many consumers. Further, the proposed technology will have the potential to produce customized rGelatin for specific applications.

这个小型技术转移研究（STTR）第一阶段项目将评估用于生产重组明胶（rGelatin）的水稻细胞培养系统，该系统旨在改善胶囊性能。该项目的商业应用将服务于制药行业的胶囊制造商。与其他重组平台相比，用于创建rGelatin的植物系统将提供更低成本的生产系统。这种重组产品将比动物来源的明胶更安全，并且更容易被许多消费者接受。此外，所提出的技术将有可能为特定应用生产定制的rGelatin。