IGERT Proposal - Integrated Training in the Evolution of Development

新颖的形式和功能的持续起源是地球上生命的特征。虽然变化发生在种群内部，但它们会改变基因组，从而改变个体的发育。虽然进化论、发育生物学和基因组学是理解生命不可或缺的组成部分，但实际上，目前所有的研究生导师本身都受过专门的人口生物学家、胚胎学家、分子生物学家或计算机科学家的正式培训。该计划的跨学科研究主题是通过结合俄勒冈州大学和印第安纳州大学的专业知识，培养研究生调查进化，发展，基因组学和生物信息学界面上出现的问题。该计划的智力重点是询问新结构和功能的发展如何随着时间的推移在人群中演变，以及伴随发展创新演变的基因组变化机制是什么？创新的教育和培训功能整合了跨学科的研究，因为学员与不同学科的共同顾问合作，参加独特的发展演变课程，并与俄勒冈州和印第安纳州大学的教师亲自和视频会议互动。培训生通过在每周EvoDevo期刊俱乐部进行批判性演讲来培养专业和个人技能，培养与各学院研究项目合作的团队合作技能，在监督的大学教学中磨练教学技能，获得与本科少数民族研究生合作的指导技能，并联系知名研究人员年度IGERT研讨会。更广泛的影响包括招聘，指导和留住代表性不足的研究生的活动，并指导来自代表性不足群体的研究生。该项目将增加训练有素的研究人员队伍，在融合的学科前沿进行研究，对理解复杂性状（包括多因素疾病），开发改良农作物以及了解我们的生物世界是如何形成的具有实际意义。IGERT是一个NSF范围内的计划，旨在满足教育美国博士的挑战。具有跨学科背景的科学家和工程师，在所选学科的深厚知识，以及未来职业需求所需的技术，专业和个人技能。该计划旨在通过建立创新的研究生教育和培训新模式，在超越传统学科界限的合作研究的肥沃环境中促进研究生教育的文化变革。

The continuing origin of novel form and function characterizes life on Earth. Although changes occur within populations, they transform genomes to alter the development of individuals. While evolution, developmental biology, and genomics are integral to understanding life, virtually all current trainers of graduate students were, themselves, formally trained exclusively as either population biologists, or embryologists, or molecular biologists, or computer scientists. This program's interdisciplinary research theme is to train graduate students to investigate emerging problems at the interface of evolution, development, genomics, and bioinformatics by combining expertise at the University of Oregon and Indiana University. The program's intellectual focus asks how development of new structures and functions evolve in populations over time, and what are the mechanisms of genome change that accompany the evolution of developmental innovations? Innovative education and training features integrate interdisciplinary research as trainees work with co-advisors in different disciplines, take unique Evolution of Development courses, and interact with faculty at the University of Oregon and Indiana University in person and in video conference. Trainees develop professional and personal skills by making critiqued presentations at weekly EvoDevo Journal Clubs, develop teamwork skills working with various faculty on research projects, hone teaching skills in supervised college teaching, gain mentoring skills working with undergraduate minority research students, and contact renowned researchers the annual IGERT symposium. Broader impacts include activities to recruit, mentor, and retain underrepresented graduate students, and the mentoring of research undergraduates from underrepresented groups. The project will increase the cadre of researchers trained to conduct research at the cutting edge of fused academic disciplines, with practical implications for the understanding of complex traits (including multifactorial diseases), the development of improved agricultural crops, and an understanding of how our biological world came to be. IGERT is an NSF-wide program intended to meet the challenges of educating U.S. Ph.D. scientists and engineers with the interdisciplinary background, deep knowledge in a chosen discipline, and the technical, professional, and personal skills needed for the career demands of the future. The program is intended to catalyze a cultural change in graduate education by establishing innovative new models for graduate education and training in a fertile environment for collaborative research that transcends traditional disciplinary boundaries.