New Aspects on Photoisomerization. Mechanistic Concepts, Medium Effects and Photosensitive Bioipigments and Materials

有了这个奖项，有机和高分子化学计划继续支持夏威夷大学化学系教授Robert Liu的工作。 该研究将扩展PI在受限介质中烯烃光异构化基本方面的研究。 该项目的重点是顺式到反式烯烃的光化学转化的Hula-Twist（HT）机制，该机制由PI发现，现在被认为在许多光生物过程中很重要。我们将进行一系列的实验来探讨取代和自旋多重性对H-T光异构化的影响。 此外，还考察了该反应的同位素效应和相对选择性。 在一系列与光生物学和材料科学中的光过程相关的实验中，将研究HT异构化在视黄醛，花青染料和吡咯基烯烃中的作用。这些烯烃光异构化的研究将提供光化学反应性的基本新信息，将对从视觉化学到材料科学的各个领域产生重大影响。 该项目提供了一个很好的方式介绍本科生一个复杂的研究计划。

With this award, the Organic and Macromolecular Chemistry Program continues its support of the work of Professor Robert Liu of the Department of Chemistry at the University of Hawaii. The research will extend the PI's investigations of the fundamental aspects of alkene photoisomerization in confined media. The focus of the project is the Hula-Twist (HT) mechanism for photochemical conversion of cis to trans alkenes, which was discovered by the PI and is now thought to be important in many photobiological processes. A series of experiments designed to explore the effect of substitution and spin multiplicity on the H-T photoisomerization will be undertaken. The regeoselectivity and the isotope effects on this reaction will also be examined. In a series of experiments that are relevant to photobiology and photoprocesses in material science, the role of HT isomerizations in retinals, cyanine dyes, and pyrrole based alkenes will be investigated. These investigations of alkene photoisomerization, which will provide fundamental new information on photochemical reactivity, will have significant impact on areas ranging from the chemistry of vision to materials science. The project provides an excellent way of introducing undergraduate students to a sophisticated research program.