CAREER: Versatile Vanadium: Materials Science, Biology, and Education Through Its Diverse Coordination Chemistry

职业：多功能钒：通过其多样化的配位化学实现材料科学、生物学和教育

• 批准号: 0645081
• 负责人: Craig McLauchlan
• 金额: $ 47.5万
• 依托单位: Board of Trustees of Illinois State University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-02-01 至 2013-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0645081&HistoricalAwards=false
• 关键词: CAREER; Versatile; Vanadium; Materials; Science

This CAREER award by the Inorganic, Bioinorganic, and Organometallic Chemistry program supports research by Dr. Craig C. McLauchlan at Illinois State University on the coordination chemistry and reactivity of vanadium with tridentate scorpionate ligands. The studies will elucidate synthetic methodologies in the preparation of these coordination complexes and examine their reactivities and properties for use in materials, catalysis, and therapeutic medicinal applications. The proposed studies should reveal novel vanadium-organophosphonate complexes and offer insight in control of dimensionality through ligand choice. The proposed work offers additional insight into the utilization of vanadium complexes as medicinal therapeutic agents by expanding the understanding of individual factors in the dominant oxidation states of these complexes under physiological conditions. The educational component of this project involves the creation of educational modules for a series of progressively complex classes on the subject of coordination chemistry involving Student Response Device (a.k.a. "clicker") technology. Professor McLauchlan will also incorporate model kits for use in improving student understanding of molecular-level structure. He will establish a mentoring network and offer workshops and free use of a student response system to interested community college faculty. Professor McLauchlan will also mentor students in the teaching/research laboratory, providing them with a broad skill set in synthesis, characterization, and X-ray training, which will prepare the students well for their futures in industry or graduate school.

这个由无机、生物无机和有机化学项目颁发的职业奖支持了克雷格C博士的研究。McLauchlan在伊利诺斯州州立大学对钒与三齿蝎形配体的配位化学和反应性进行了研究。 这些研究将阐明这些配位络合物的合成方法，并研究其在材料，催化和治疗医学应用中的反应性和性质。 拟议的研究应揭示新的钒有机膦酸盐配合物，并提供洞察力，通过配体的选择控制维数。 拟议的工作提供了额外的洞察钒配合物作为药物治疗剂的利用，通过扩大这些配合物在生理条件下的主导氧化态的个别因素的理解。 该项目的教育部分涉及为一系列涉及学生反应装置（a.k.a.）的配位化学主题逐步复杂的课程创建教育模块。“clicker”）技术。 McLauchlan教授还将结合模型工具包，用于提高学生对分子水平结构的理解。 他将建立一个指导网络，并提供研讨会和免费使用的学生反应系统感兴趣的社区学院教师。 McLauchlan教授还将在教学/研究实验室指导学生，为他们提供合成，表征和X射线培训方面的广泛技能，这将为学生在工业或研究生院的未来做好准备。