SGER: Controlled fragmentation and ionization of biological samples

SGER：生物样品的受控碎片和电离

• 批准号: 0647901
• 负责人: Marcos Dantus
• 金额: --
• 依托单位: Michigan State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-08-15 至 2009-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0647901&HistoricalAwards=false
• 关键词: SGER; Controlled; fragmentation; ionization; biological

In this SGER award, funded by the Experimental Physical Chemistry Program, Prof. Marcos Dantus of Michigan State University and his graduate and undergraduate student colleagues will conduct exploratory research in the attempt to develop the controlled fragmentation and detection of ionized biological species in the gas phase. They propose to do this through the use of shaped femtosecond laser pulses.Prof. Dantus and his group will attempting to use shaped ultrafast laser pulses to selectively fragment large biological ions in the gas phase. The ultimate aim of these studies is to obtain structural information of large biomolecules with a programmable laser source. The major impact of this type of instrument would be in biological research. The graduate and undergraduate students working on this will receive stellar training in research that is at the interface of physical and biological science.

在这项由实验物理化学项目资助的SGER奖项中，密歇根州立大学的Marcos Dantus教授及其研究生和本科生同事将进行探索性研究，试图开发电离生物物种的受控碎片化和检测。在气相中。 Dantus教授和他的团队将尝试使用成形的超快激光脉冲来选择性地碎裂气相中的大型生物离子。 这些研究的最终目的是用可编程激光源获得大生物分子的结构信息。 这类仪器的主要影响将是在生物研究方面。 研究生和本科生在这方面的工作将接受恒星的研究是在物理和生物科学的接口培训。