RUI: Stochastic models in population biology

RUI：群体生物学中的随机模型

• 批准号: 0701396
• 负责人: Rinaldo Schinazi
• 金额: $ 10.21万
• 依托单位: University of Colorado at Colorado Springs
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-07-15 至 2011-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0701396&HistoricalAwards=false
• 关键词: RUI; Stochastic; models; population; biology

Rinaldo Schinazi proposes new probability models in population biology. The models are spatial (interacting particle systems) or non spatial. A special effort is made to formulate models simple enough so that rigorous analysis is possible but still interesting and relevant to the biological questions. Models introduced by Schinazi often generate new and interesting mathematical questions.Rinaldo Schinazi proposes to study theoretical population biology questions using probability models. The starting point is always a concrete question such as: "Does a low mutation rate for stem cells protect from cancer?" or "Can the immune system be overwhelmed by a particular virus only because of its high mutation rate?" The end point is the testing of biology hypotheses or the formulation of new hypotheses.

Rinaldo Schinazi在种群生物学中提出了新的概率模型。模型是空间的（相互作用的粒子系统）或非空间的。一个特别的努力是制定足够简单的模型，以便严格的分析是可能的，但仍然是有趣的和相关的生物学问题。Schinazi引入的模型经常产生新的和有趣的数学问题。Rinaldo Schinazi建议使用概率模型来研究理论种群生物学问题。出发点总是一个具体的问题，比如：“干细胞的低突变率是否能预防癌症？”或者“免疫系统能否仅仅因为某种特定病毒的高突变率而被其击垮？”研究的终点是检验生物学假说或提出新的假说。