Targeted Infusion Grant: Enhancing the Undergraduate Biochemistry Experience by Implementing a Concentration in Biochemistry within the Chemistry Program

生物技术的进步和创新在北卡罗来纳州和东海岸生物科学和生物技术中心的经济发展中促进了重要的生物科学研究和商业。在全国范围内，生物技术的影响，特别是对人类基因组的绘制和这种技术进步的应用，在这个国家的经济发展中发挥了重要作用。这为化学专业的学生提供了一个扩大职业选择的机会，尤其是在温斯顿-塞勒姆州立大学（WSSU），这所大学位于皮埃蒙特三合会地区，是生物科学的主要参与者。这个有针对性的输液项目的目标是在WSSU现有的化学课程中实施生物化学浓度，以提高生物化学经验的本科课程。生物科学在研究和工业中的明显影响创造了提供生物化学选择的需求，这不仅是为了确保学生的跨学科指导和研究训练，也是为了吸引更多的少数民族学生进入这一科学学科。这些努力还将支持该机构目前的举措，以履行其经济发展作用。这个定向输液项目的目标是：(i)实施acs认可的化学学位课程，并开设生物化学课程；（ii）将先进的生物技术融入生物化学实验室教学大纲；（iii）提供仪器支持先进的生物化学技术，确保教学、培训和研究工作的连续性，使学生对生物科学研究和工业中使用的技术有更敏锐的洞察力。长期目标是在华盛顿州立大学建立跨学科的生物化学学位课程。这个项目的智力价值包括让学生准备好应对生化和生物研究和工业的最新趋势，为化学系的研究基地做出贡献，并进一步让学生接触跨学科的研究性质。提议的高级生物化学实验室结合了绿色荧光蛋白的统一主题，最终通过圆二色性进行结构和稳定性研究，这是该项目的创新部分。实施实验的模块化顺序将在高级生物化学实验室提供统一的学习体验。这个项目更广泛的影响包括促进经济发展，培养高素质的学生，以满足我们社会的需要，这个社会越来越依赖于科学技术的进步。本项目为加强本科生生物化学经验而制定的课程改进将在适当的期刊上发表，在地方和国家会议上传播，并在两个系的网站上免费提供，以促进教学、培训和学习。WSSU STEM项目的预期成果包括增加化学和生物化学科学专业的毕业生人数，包括代表性不足的少数民族学生。

Advances and innovations in biotechnology have promoted significant bioscience research and business in the economic development of North Carolina, and the east coast bioscience and biotechnology centers. Nationwide, the impact of biotechnology, especially on the mapping of the human genome and the applications of such technological advances, has played a significant role in the economic development of this nation. This creates an opportunity to expand the career options for chemistry majors, especially at Winston-Salem State University (WSSU), which is located in the Piedmont Triad region, a major player in bioscience. The goal of this targeted infusion project is to implement a Concentration in Biochemistry within the existing chemistry program at WSSU to enhance the undergraduate curriculum in biochemistry experience. The evident impact of bioscience in research and industry creates a need to offer this biochemistry option not only to ensure interdisciplinary instructions and research training for students, but also to attract more minority students to this scientific discipline. These efforts will also support current initiatives at this institution to fulfill its economic development role. The objectives of this targeted infusion project are; (i) to implement an ACS-Approved Chemistry degree program with a Biochemistry Track, (ii) to adapt and integrate advanced techniques in biotechnology into the biochemistry laboratory instructions, and (iii) to provide instrumentation to support advanced biochemistry techniques that will secure the necessary continuum in instruction, training, and research efforts, for preparing students to be more perceptive to techniques used in bioscience research and industry. The long term goal is to establish an interdisciplinary biochemistry degree offering at WSSU. The intellectual merits of this project include preparing students in response to recent trends in biochemical and biological research and industry, contribute to the research base at the Chemistry Department, and further expose students to the interdisciplinary nature of research. The proposed advanced biochemistry laboratory incorporating a unifying theme on the green fluorescent protein culminating in the structural and stability studies by Circular Dichroism is an innovative part of this project. The modular sequence of the implemented experiments will provide a unified learning experience in the advanced biochemistry laboratory. The broader impacts of this project include the promotion of economical development in quality students to meet the needs of our society, which is increasingly dependent on advances made in science and technology. The curricular enhancement developed in this project to strengthen the undergraduate biochemistry experience will be published in appropriate journals, disseminated at local and national meetings, and made freely available via websites of both departments to promote teaching, training, and learning. An anticipated outcome of this project on the STEM program at WSSU includes an increase in the number of graduates, including underrepresented minority students, in the chemical and biochemical sciences.