High-Resolution Integrated Ultrasound and Microwave Imaging for Early-Stage Breast Cancer Diagnosis

用于早期乳腺癌诊断的高分辨率集成超声和微波成像

• 批准号: 0756338
• 负责人: Fawwaz Ulaby
• 金额: $ 30万
• 依托单位: Regents of the University of Michigan - Ann Arbor
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-05-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0756338&HistoricalAwards=false
• 关键词: Resolution; Integrated; Ultrasound; Microwave; Imaging

CBET-0756338, MoghaddamThe PI proposes combining two non-ionizing imaging modalities, ultrasound and microwave, to take advantage of the synergistic imaging properties that result. The ultrasound component will provide information regarding shape and location of unidentified tissue masses. The microwave component utilizes nonlinear time domain inverse scattering techniques and would provide quantitative information regarding the dielectric constant and conductivity of the tissue. Unlike the current systems that require verification, the proposed imaging system could provide a definitive diagnosis of the tissue mass /lesion significantly reducing the percent of false positive and false negative reports. When used in combination with the ultrasound shape functions it could provide an imaging system with increased resolution, spatial fidelity, and ability to quantify and characterize the tissue type. Initially the US and MW measurements will be taken simultaneously and independently during the early stages of algorithm development. The proposed imaging system could possibly provide a resolution of less than 5mm.

CBET-0756338，Moghaddam PI 建议结合两种非电离成像模式（超声波和微波），以利用由此产生的协同成像特性。超声组件将提供有关未识别组织块的形状和位置的信息。微波组件利用非线性时域逆散射技术，并提供有关组织介电常数和电导率的定量信息。与需要验证的当前系统不同，所提出的成像系统可以提供组织块/病变的明确诊断，显着降低假阳性和假阴性报告的百分比。当与超声形状函数结合使用时，它可以提供具有更高分辨率、空间保真度以及量化和表征组织类型的能力的成像系统。最初，US 和 MW 测量将在算法开发的早期阶段同时独立进行。所提出的成像系统可能提供小于 5 毫米的分辨率。