INTERNATIONAL - Isotopic Perturbation of Methyl Rotation in Carbocations

国际 - 碳阳离子中甲基旋转的同位素扰动

• 批准号: 0809780
• 负责人: Martin Saunders
• 金额: $ 9万
• 依托单位: Yale University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-07-15 至 2012-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0809780&HistoricalAwards=false
• 关键词: INTERNATIONAL; Isotopic; Perturbation; Methyl; Rotation

Probably the most important topic to be investigated under this grant is the proposed new extension of the NMR isotopic perturbation method (which originated in the Saunders Laboratory and has been applied to many problems involving carbocation structures and rearrangements) to cases where the rotation of a methyl group is isotopically perturbed. This innovation will have a number of important applications outside of the field of carbocations. It is expected that this method will be used to probe subtle differences on the non-equivalent CH bonds to methyl groups in environments of less than three-fold symmetry. The broader impacts are addressed by the expectation of having student involvement (including women) from Croatia and from Yale. It is expected that participation in the work supported by this grant would be a substantial aid to their education.

根据这笔赠款，可能要研究的最重要的主题是提议将核磁共振同位素微扰法(起源于桑德斯实验室，已被应用于许多涉及碳正离子结构和重排的问题)扩展到甲基的旋转受到同位素扰动的情况。这项创新将在碳阳离子领域之外有许多重要的应用。预计这种方法将被用来探索在不到三重对称性的环境中，甲基与非等价CH键的细微差异。更广泛的影响是通过预期克罗地亚和耶鲁的学生(包括女性)的参与来解决的。预计参加这笔赠款支持的工作将对他们的教育有很大的帮助。