MRI: Acquisition of a MicroCT System for Collaborative Research at UMBC

CBET-0821236 ZhuMicroCT是一种采用断层扫描的高分辨率、非破坏性成像方法，其中连续X射线扫描的数字处理用于生成对象结构的3D图像。它已成为研究的典型工具，需要非侵入性表征的内部形态和识别不同的阶段。该提案描述了microCT在研究硬组织和软组织、生物材料和工程微材料的微结构与物理特性之间的关系方面的独特应用。本研究的具体目的是：1。详细描述肿瘤血管系统和眼部结构与眼部疾病的关系。评估随着年龄增长和/或疾病的硬组织和软组织的微观结构变化。描述渗透性天然材料和先进结构材料的传输特性。

CBET-0821236ZhuMicroCT is a high resolution, non-destructive imaging method that employs tomography, where digital processing of sequential x-ray scans is used to generate a 3-D image of an object's structure. It has become the quintessential tool for research requiring non-invasive characterization of internal morphology and identification of disparate phases. This proposaldescribes unique applications of microCT in conducting research on relationships betweenmicrostructure and the physical properties of hard and soft tissues, biomaterials, and engineered micro-materials. The specific aims of the proposed research are to:1. Detail the vasculature in tumors and structures of the eye associated with ocular diseases.2. Evaluate microstructural changes in hard and soft tissues with aging and/or diseases.3. Characterize transport in permeable natural materials and advanced structural materials.