MRI: Acquisition of a MicroCT System for Collaborative Research at UMBC

CBET-0821236诸微CT是一种采用层析成像的高分辨率、非破坏性成像方法，其中使用顺序X射线扫描的数字处理来生成物体结构的3-D图像。它已经成为需要非侵入性表征内部形态和识别不同相的研究的典型工具。这项提议描述了微CT在研究硬组织和软组织、生物材料和工程微材料的微结构和物理性能之间的关系方面的独特应用。拟议研究的具体目的是：1.详细描述与眼部疾病相关的眼部肿瘤和结构中的血管。评估衰老和/或疾病对硬组织和软组织微结构的影响。描述渗透性天然材料和先进结构材料中的传输特性。

CBET-0821236ZhuMicroCT is a high resolution, non-destructive imaging method that employs tomography, where digital processing of sequential x-ray scans is used to generate a 3-D image of an object's structure. It has become the quintessential tool for research requiring non-invasive characterization of internal morphology and identification of disparate phases. This proposaldescribes unique applications of microCT in conducting research on relationships betweenmicrostructure and the physical properties of hard and soft tissues, biomaterials, and engineered micro-materials. The specific aims of the proposed research are to:1. Detail the vasculature in tumors and structures of the eye associated with ocular diseases.2. Evaluate microstructural changes in hard and soft tissues with aging and/or diseases.3. Characterize transport in permeable natural materials and advanced structural materials.