Collaborative Research: Center for Pharmaceutical Manufacturing and Formulation

合作研究：药品制造和制剂中心

• 批准号: 0832469
• 负责人: Andreas Bommarius
• 金额: $ 1万
• 依托单位: Georgia Tech Research Corporation
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-08-15 至 2010-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0832469&HistoricalAwards=false
• 关键词: Collaborative; Research; Center; Pharmaceutical; Manufacturing

Planning Grant for an I/UCRC for Pharmaceutical Manufacturing and Formulation 0832469 Georgia Tech; Andreas Bommarius 0832530 University of Kansas; Eric Munson 0832478 Duquesne University; James Drennen Georgia Institute of Technology, University of Kansas, and Duquesne University propose a planning grant for a collaborative center "Center for Pharmaceutical Manufacturing and Formulation (CPMF)" to address current challenges in the pharmaceutical industry with the aim of developing solutions towards more selective and robust manufacturing processes, more stable formulations, and better characterized and consistent products. The Center will provide a mechanism for collaborative projects between scientists from government, academia, and industry to develop innovative methods towards more selective and robust processes with less environmental footprint and to improve the safety of the nations drug supply. The proposed research agenda includes manufacturing, formulation, and analytical. The manufacturing focus is on transitioning to microscale and continuous process from the current norm of batch processes. The integration of manufacturing, formulation, and analyses of the approaches to testing and rapid identification of counterfeit and degraded drugs will lead to an advancement in knowledge in the field. Advances in these areas would help mitigate production costs, and would help keep the companies viable. The proposed work will improve the ability to develop safe drugs and drug formulations. Collaborations with the pharmaceutical industry will add value by promoting the rapid dissemination and application of technologies and information. The proposed center (CPMF) will promote learning by participant students as they conduct their research. CPMF will also place emphasis on recruiting under-represented groups in the graduate education, including presentations and visits to colleges and universities that serve under-represented groups, especially where the faculty are alumni.

用于药品制造和配方的 I/UCRC 规划拨款 0832469 佐治亚理工学院；安德烈亚斯·博马留斯 0832530 堪萨斯大学；埃里克·蒙森 0832478 杜肯大学； James Drennen 佐治亚理工学院、堪萨斯大学和杜肯大学提议为合作中心“药品制造和配方中心 (CPMF)”提供规划拨款，以应对制药行业当前的挑战，旨在开发解决方案，实现更具选择性和稳健的制造工艺、更稳定的配方以及更好的特性和一致性产品。该中心将为来自政府、学术界和工业界的科学家之间的合作项目提供一个机制，以开发创新方法，以实现更具选择性和稳健的工艺，减少环境足迹，并提高国家药品供应的安全性。拟议的研究议程包括制造、配方和分析。制造重点是从当前的批量工艺规范过渡到微型和连续工艺。假冒和降解药物的测试和快速识别方法的制造、配方和分析的整合将导致该领域知识的进步。这些领域的进步将有助于降低生产成本，并有助于保持公司的生存能力。拟议的工作将提高开发安全药物和药物制剂的能力。 与制药行业的合作将通过促进技术和信息的快速传播和应用来增加价值。 拟议的中心（CPMF）将促进参与学生在进行研究时的学习。 CPMF 还将强调在研究生教育中招募代表性不足的群体，包括对为代表性不足的群体服务的学院和大学进行演讲和访问，特别是那些教师是校友的学院和大学。