IWGSC-IBSC Workshop on Genome Sequencing Strategies

下一代DNA测序技术的最新进展为在合理的时间框架内以可处理的成本处理大的复杂基因组（如小麦和大麦）打开了前景。现在讨论利用这些技术对小麦和大麦基因组进行测序是及时的。 为此，国际小麦基因组测序联盟（www.example.com）和国际大麦测序联盟（www.example.com）将召开一次关于小麦（Triticum aestivum L.）和大麦（Hordeum vulgare L.）基因组测序 讲习班的目标是：- 提供小麦和大麦基因组结构的概述-确定测序小麦和大麦的要求和挑战-讨论策略，成功，以及已完成的动物和具有重要经济意义的植物基因组测序项目的失败-讨论正在进行的小麦和大麦试点研究的结果，这些研究单独使用新技术或与桑格测序技术相结合-从新测序技术平台的开发人员那里获得关于如何将其技术应用于大型复杂基因组测序的信息，例如小麦和大麦的研究-发现处理这些项目的生物信息学方面的需求和机会-讨论国家和国际资助机会-确定新技术是否可以在不久的将来用于基因组测序，以及应该开发哪些项目来评估这种可能性-制定未来几年小麦和大麦基因组测序的战略路线图。本次研讨会将汇集人类和农业重要基因组测序项目的国际专家，基因组测序技术的开发人员，对小麦和大麦基因组结构和组织有广泛了解的科学家，对植物物种从头测序感兴趣的国际基因组测序中心的代表，以及政府资助机构的代表。 研讨会将持续两天，并将产生一份总结文件，分发给所有与会者以及对小麦和大麦基因组学进展感兴趣的其他人。

The recent advances in the development of next generation DNA sequencing technologies are opening the prospect for tackling large, complex genomes such as wheat and barley in a reasonable time frame and for tractable cost. It is timely to discuss the use of these technologies to sequence the wheat and barley genomes. To this end, the International Wheat Genome Sequencing Consortium (www.wheatgenome.org) and the International Barley Sequencing Consortium (www.barleygenome.org) will convene an international workshop on wheat (Triticum aestivum L.) and barley (Hordeum vulgare L.) genome sequencing. The goals of the workshop are to: - Provide an overview of the wheat and barley genome structure- Identify the requirements and challenges of sequencing wheat and barley- Discuss the strategies, successes, and failures of completed animal and economically-important plant genome sequencing projects- Discuss the results of ongoing wheat and barley pilot studies using new technologies alone or in combination with Sanger sequencing technology- Gain input from the developers of new sequencing technology platforms on how to apply their technologies to sequence large, complex genomes, such as those of wheat and barley- Discern needs and opportunities in bioinformatics to handle these projects- Discuss national and international funding opportunities- Determine whether the new technologies can be used to sequence the genomes in the near future and which projects should be developed to evaluate this possibility- Establish a strategic roadmap for sequencing the wheat and barley genomes in the next few years.This workshop will bring together international experts in the human and agriculturally-important genome sequencing projects, developers of genome sequencing technologies, scientists with extensive knowledge of the structure and organization of the wheat and barley genomes, representatives of international genome sequencing centers interested in de novo sequencing of plant species, as well as representatives of governmental funding agencies. The workshop will last two days and will result in a summary document that will be distributed to all participants as well as others interested in advances in wheat and barley genomics.