CAREER: Dynamic Surface Gradients for Studies of Cell Polarization and Cell Migration
CAREER: Dynamic Surface Gradients for Studies of Cell Polarization and Cell Migration
批准号:
0846843
负责人:
Muhammad Yousaf
金额:
$60.0万
依托单位国家:
美国
项目类别:
Continuing Grant
财政年份:
2009
资助国家:
美国
项目状态:
已结题
起止时间:
2009-02-01 至 2011-08-31
中文摘要
化学系(CHE)的分析和表面化学课程以及分子和细胞生物学系(MCB)的细胞系统课程将支持Muhammad N.位于查佩尔山的北卡罗来纳州大学化学系的尤萨夫说。Yousaf教授和他的学生将开发一类电活性和动态表面,以研究细胞极性和细胞迁移。 微流体和高分辨率活细胞荧光显微镜技术沿着与遗传编码的生物传感器将被用来产生动态表面梯度,以研究在定向细胞迁移过程中的内部信号。 这项研究将为研究生和本科生提供多学科培训。Yousaf教授还将把微流体和生物相关系统的表面表征研究与教育活动相结合,这些教育活动的重点是与当地一所大学进行研究和指导活动的交流,以满足服务不足的少数群体的需要。
英文摘要
The Analytical and Surface Chemistry Program of the Division of Chemistry (CHE)and the Cellular Systems program of the Division of Molecular and Cell Biology (MCB)will support the CAREER development plan of Prof. Muhammad N. Yousaf of the Department of Chemistry at the University of North Carolina at Chapel Hill. Prof. Yousaf and his students will develop a class of electroactive and dynamic surfaces to study cell polarity and cell migration. Microfluidic and high-resolution live-cell fluorescence microscopy techniques along with genetically encoded biosensors will be used to generate dynamic surface gradients to study internal signaling during directed cell migration. The research will provide multidisciplinary training for graduate and undergraduate students. Prof. Yousaf also will integrate research in microfluidics and surface characterization of biologically relevant systems with educational activities focused on implementing the exchange of research and mentoring activities with a local university that caters to underserved minority groups.
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国内基金
海外基金
Dynamic Credit Rating with Feedback Effects
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项目类别:外国学者研究基金项目
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批准年份:2024
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负责人:Christian Martin Hilpert
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依托单位: