SBIR Phase I: Increasing Productivity of Microalgae for Biodiesel.

SBIR 第一阶段：提高微藻生产生物柴油的生产力。

• 批准号: 0911889
• 负责人: Walter Messier
• 金额: $ 9.96万
• 依托单位: Evolutionary Genomics, LLC
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-07-01 至 2010-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0911889&HistoricalAwards=false
• 关键词: SBIR; Phase; Increasing; Productivity; Microalgae

This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).This Small Business Innovation Research Phase I project makes use of expertise derived from the intersection of molecular biology and evolutionary biology to identify genes that control lipid (i.e., oil) accumulation in microalgae. The genes will be validated for their role in controlling lipid accumulation and will then be used to produce custom strains of algae that are highly productive. The biggest limitation to commercial use of microalgae to produce biodiesel is productivity: lipid accumulation needs to be improved. Successful identification of genes that increase lipid production will be followed in Phase II by use of these genes to develop improved microalgae strains for sale to commercial partners. The broader impacts of this research are both commercially and for American society at large. A major problem of the 21st century will be to produce sufficient environmentally benign fuel for the U.S. population. Dependence on finite, non-renewable petroleum for transportation fuels is at the heart of many of the challenges we are now facing, including soaring energy costs, unpredictable foreign oil markets with resultant national security threats, and environmental deterioration. World energy demands will only be met with a diversity of energy products. Microalgae can produce far greater amounts of lipids per acre than other lipid sources. The biggest current limitation to commercial use of microalgae to produce biodiesel is productivity: lipid accumulation needs to be improved, which is the goal of this project.

该奖项是根据2009年《美国复苏和再投资法案》(公法111-5)资助的。这个小型企业创新研究第一阶段项目利用分子生物学和进化生物学交叉产生的专业知识来识别控制微藻中脂肪(即油)积累的基因。这些基因将被验证它们在控制脂肪积累方面的作用，然后将被用来制造出高产量的定制藻类菌株。微藻用于生产生物柴油的商业使用的最大限制是生产率：需要改善脂肪积累。在第二阶段中，将通过使用这些基因来开发销售给商业合作伙伴的改良微藻菌株，从而成功地识别出增加脂肪生产的基因。这项研究的更广泛影响既是商业上的，也是对整个美国社会的。21世纪的一个主要问题将是为美国民众生产足够的环保燃料。对有限的、不可再生的石油作为运输燃料的依赖是我们现在面临的许多挑战的核心，包括能源成本飙升、不可预测的外国石油市场随之而来的国家安全威胁以及环境恶化。只有多样化的能源产品才能满足世界能源需求。微藻每英亩产生的脂类比其他脂类来源多得多。目前微藻商业化生产生物柴油的最大限制是生产率：需要改善脂肪积累，这是本项目的目标。