MRI: Acquisition of a Transmission Electron Microscope for the Core, Multi-User Microscopy Facility at Appalachian State University

MRI：为阿巴拉契亚州立大学的核心多用户显微镜设施采购透射电子显微镜

• 批准号: 0922697
• 负责人: Guichuan Hou
• 金额: $ 50.96万
• 依托单位: Appalachian State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-08-01 至 2012-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0922697&HistoricalAwards=false
• 关键词: MRI; Acquisition; Transmission; Electron; Microscope

The Dewel Microscopy Facility (DMF) in the College of Arts & Sciences at Appalachian State University (ASU) is using a new transmission electron microscope (TEM) to improve and enhance faculty, staff, and student research and teaching at ASU and in western North Carolina. A TEM is an essential tool for studying internal cellular and ultra-structures of animal and plant tissues, as well as microorganisms. It also is very important for teaching and research in many other scientific disciplines, including physics, chemistry, geology and materials science. The acquired instrument is the JEOL JEM-1400 TEM. The DMF is a core, multi-user microscopy facility for all Appalachian State University departments as well as community colleges, high schools and industry in the Appalachian region of western North Carolina. Some of the immediate applications where this instrumentation has significant impact for researchers include investigation of the roles of microtubules in root development and morphogenesis; localization of plant stem cells producing reactive oxygen species under high light stress; characterization of microvascular alterations during cervical remodeling in mice; ultrastructural localization of proteins in the gills of fishes; and studies of metallic nanostructures on end-faces of optical fibers for chemical sensing applications. In addition, this new TEM will significantly improve the teaching quality of biology and physics microscopy courses at Appalachian State University.Appalachian State University is a fast growing public university located in western North Carolina, many of whose students are first generation college attendees. Therefore, one of the main goals in the application of this new instrumentation is to train many motivated undergraduate students across biology, physics, chemistry, geology, and other disciplines. The new TEM will also play a vital role in several current outreach programs, including the Appalachian Student Experience-based Education (AppalSEED) Academy, which is a year-long program and focuses on training home-schooled students and high school students from underrepresented groups, including women and African-American students, in western North Carolina. Lastly, the new TEM will enhance service capabilities of the DMF for the surrounding communities and further strengthen collaborations among biologists, physicists, and other scientists, as well as faculty and students at other universities in western North Carolina. The project outcomes are available for public viewing on a dedicated page at the DMF website (http://www.casmifa.appstate.edu/index.html).

阿巴拉契亚州立大学（ASU）艺术科学学院的Dewel显微镜设施（DMF）正在使用一种新的透射电子显微镜（TEM）来改善和加强ASU和北卡罗来纳州西部的教师、员工和学生的研究和教学。TEM是研究动植物组织以及微生物内部细胞和超微结构的重要工具。它对物理学、化学、地质学、材料科学等学科的教学和研究也有重要意义。所用仪器为JEOL JEM-1400 TEM。DMF是阿巴拉契亚州立大学所有部门以及社区学院、高中和北卡罗来纳州西部阿巴拉契亚地区工业的核心多用户显微镜设施。该仪器对研究人员产生重大影响的一些直接应用包括：研究微管在根发育和形态发生中的作用;在强光胁迫下产生活性氧的植物干细胞的定位;小鼠宫颈重塑过程中微血管改变的表征;鱼类鳃中蛋白质的超微结构定位;以及用于化学传感应用的光纤端面上的金属纳米结构的研究。此外，这一新的TEM将显著提高阿巴拉契亚州立大学生物学和物理显微镜课程的教学质量。阿巴拉契亚州立大学是一所快速发展的公立大学，位于北卡罗来纳州西部，其许多学生都是第一代大学入学者。因此，在这种新的仪器应用的主要目标之一是培养跨生物学，物理学，化学，地质学和其他学科的许多积极的本科生。新的TEM还将在目前的几个推广计划中发挥至关重要的作用，包括阿巴拉契亚学生体验教育（AppalSEED）学院，这是一个为期一年的计划，重点是培训家庭教育的学生和高中学生，来自代表性不足的群体，包括妇女和非洲裔美国学生，在北卡罗来纳州西部。最后，新的TEM将增强DMF对周边社区的服务能力，并进一步加强生物学家、物理学家和其他科学家以及北卡罗来纳州西部其他大学的教师和学生之间的合作。项目成果可在灾害管理机制网站（http：//www.casmifa.appstate.edu/index.html）的专门网页上查阅。