MRI: Acquisition of a Transmission Electron Microscope for the Core, Multi-User Microscopy Facility at Appalachian State University

阿巴拉契亚州立大学(ASU)艺术与科学学院的Dewel显微镜设备(DMF)正在使用一种新的透射电子显微镜(TEM)来改善和加强亚利桑那州立大学和北卡罗来纳州西部的教职员工和学生的研究和教学。透射电子显微镜是研究动植物组织以及微生物内部细胞和超微结构的重要工具。它对许多其他科学学科的教学和研究也非常重要，包括物理、化学、地质学和材料科学。获得的仪器是JEOL JEM-1400型瞬变电磁仪。DMF是阿巴拉契亚州立大学所有院系以及北卡罗来纳州西部阿巴拉契亚地区的社区大学、高中和工业的核心多用户显微镜设施。这种仪器对研究人员有重大影响的一些直接应用包括：调查微管在根发育和形态发生中的作用；高光胁迫下产生活性氧物种的植物干细胞的定位；小鼠颈部重塑过程中微血管变化的特征；鱼鳃蛋白质的超微结构定位；以及用于化学传感应用的光纤端面的金属纳米结构的研究。此外，这一新的电子显微镜将显著提高阿巴拉契亚州立大学生物和物理显微镜课程的教学质量。阿巴拉契亚州立大学是一所快速发展的公立大学，位于北卡罗来纳州西部，许多学生是第一代大学学生。因此，应用这一新仪器的主要目标之一是培养一批积极进取的本科生，涵盖生物、物理、化学、地质等学科。新的TEM还将在目前的几个外展项目中发挥重要作用，包括阿巴拉契亚学生体验教育(AppalSEED)学院，这是一个为期一年的项目，重点是培训北卡罗来纳州西部在家接受教育的学生和来自代表性不足群体的高中生，包括女性和非裔美国学生。最后，新的TM将增强DMF为周围社区提供服务的能力，并进一步加强生物学家、物理学家和其他科学家以及北卡罗来纳州西部其他大学的教职员工和学生之间的合作。项目成果可在DMF网站(http://www.casmifa.appstate.edu/index.html).)的专用页面上供公众查看

The Dewel Microscopy Facility (DMF) in the College of Arts & Sciences at Appalachian State University (ASU) is using a new transmission electron microscope (TEM) to improve and enhance faculty, staff, and student research and teaching at ASU and in western North Carolina. A TEM is an essential tool for studying internal cellular and ultra-structures of animal and plant tissues, as well as microorganisms. It also is very important for teaching and research in many other scientific disciplines, including physics, chemistry, geology and materials science. The acquired instrument is the JEOL JEM-1400 TEM. The DMF is a core, multi-user microscopy facility for all Appalachian State University departments as well as community colleges, high schools and industry in the Appalachian region of western North Carolina. Some of the immediate applications where this instrumentation has significant impact for researchers include investigation of the roles of microtubules in root development and morphogenesis; localization of plant stem cells producing reactive oxygen species under high light stress; characterization of microvascular alterations during cervical remodeling in mice; ultrastructural localization of proteins in the gills of fishes; and studies of metallic nanostructures on end-faces of optical fibers for chemical sensing applications. In addition, this new TEM will significantly improve the teaching quality of biology and physics microscopy courses at Appalachian State University.Appalachian State University is a fast growing public university located in western North Carolina, many of whose students are first generation college attendees. Therefore, one of the main goals in the application of this new instrumentation is to train many motivated undergraduate students across biology, physics, chemistry, geology, and other disciplines. The new TEM will also play a vital role in several current outreach programs, including the Appalachian Student Experience-based Education (AppalSEED) Academy, which is a year-long program and focuses on training home-schooled students and high school students from underrepresented groups, including women and African-American students, in western North Carolina. Lastly, the new TEM will enhance service capabilities of the DMF for the surrounding communities and further strengthen collaborations among biologists, physicists, and other scientists, as well as faculty and students at other universities in western North Carolina. The project outcomes are available for public viewing on a dedicated page at the DMF website (http://www.casmifa.appstate.edu/index.html).