MRI: Acquisition of a Quartz Crystal Microbalance and a Dynamic Light Scattering Apparatus for Undergraduate Education

MRI：为本科教育购置石英晶体微天平和动态光散射仪

• 批准号: 0922834
• 负责人: Jeffrey Petty
• 金额: $ 26.09万
• 依托单位: Furman University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-15 至 2012-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0922834&HistoricalAwards=false
• 关键词: MRI; Acquisition; Quartz; Crystal; Microbalance

This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).With this award from the Major Research Instrumentation Program (MRI), Jeffrey T. Petty, Karen L. Buchmueller and Timothy W. Hanks of Furman University will acquire a quartz crystal microbalance and a dynamic light scattering apparatus. The primary research applications of the instruments will be: (1) characterization and supramolecular assembly of Janus nanoparticles, (2) surface modification of polypyrrole films for biosensor construction, (3) measurement of the competition between small molecules and proteins for DNA binding sites, and (4)investigation of how Ag+ influences the aggregation of the ribonucleotide guanosine 5-monophosphate (5GMP).The quartz microbalance measures mass changes with a sensitivity that is ~100 times greater than an electronic balance. It will be used to monitor the structural, thermodynamic, and kinetic changes that accompany association reactions. The dynamic light scattering instrument will exploit the efficient scattering of visible light by nanostructures to understand how local molecular interactions drive the assembly of larger scale assemblies. Besides Furman faculty, three faculty mentors and their students from local technical and community colleges and an industrial collaborator will participate in the research program at Furman and use the instruments. This research environment will serve as the testing ground for innovations in the physical chemistry, biochemistry, and materials science courses that emphasize structural and thermodynamic analysis of molecular interactions.

该奖项是根据2009年美国复苏和再投资法案（公法111-5）资助。凯伦·佩蒂作者声明：Timothy W.弗曼大学的汉克斯将获得一个石英晶体微量天平和一个动态光散射装置。 仪器的主要研究应用将是：（1）Janus纳米颗粒的表征和超分子组装，（2）用于生物传感器构建的聚吡咯膜的表面修饰，（3）小分子和蛋白质之间对DNA结合位点的竞争的测量，（4）Ag+对5-磷酸鸟苷（5GMP）聚集的影响石英微量天平测量质量变化的灵敏度比电子天平高约100倍。 它将用于监测伴随缔合反应的结构、热力学和动力学变化。动态光散射仪器将利用纳米结构对可见光的有效散射，以了解局部分子相互作用如何驱动更大规模组件的组装。 除了弗曼教师，三名教师导师和他们的学生从当地的技术和社区学院和工业合作者将参加在弗曼的研究计划，并使用仪器。这个研究环境将作为物理化学，生物化学和材料科学课程创新的试验场，强调分子相互作用的结构和热力学分析。