GSC 1091: Berlin School of Integrative Oncology (BSIO)

GSC 1091：柏林综合肿瘤学院 (BSIO)

• 批准号: 194676614
• 金额: --
• 依托单位: Freie Universität Berlin
• 依托单位国家: 德国
• 项目类别: Graduate Schools
• 财政年份: 2012
• 资助国家: 德国
• 起止时间: 2011-12-31 至 2018-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/194676614?language=en
• 关键词: GSC; 1091; Berlin; Integrative; Oncology

Educational and career-related goals of the Berlin School of Integrative Oncology (BSIO) are: (1) to enthuse pupils and undergraduate students for cancer research and a scientific career, (2) to educate basic scientists and (future) clinicians in a joint fashion in translational cancer research (with the goal that they "speak the same language"), (3) to point out the clinical presentation and the most urgent problems in oncology to basic scientists, (4) to enable clinicians to obtain a "Dr. rer. nat." (PhD) in order to create a common language between basic scientists and clinicians, (5) to provide programmes in doctoral education that match a candidates individual career profile, (6) to augment the international experience of graduate students during their PhD, (7) to offer a comprehensive supervision concept, (8) to ensure a "seamless" career programme ranging from undergraduate studies to the first independent position, (9) to facilitate the critical transition phases during early career development, (10) to re-attract the best BSIO graduates after they have completed their first postdoctoral position(s) at other institutions.Structural goals are: (1) to guide graduate students in a highly efficient fashion through their PhD project while following highest quality standards, (2) to facilitate studying and working at a multi-institutional metropolitan region, (3) to enlarge and to enhance existing structures in cancer research.

柏林综合肿瘤学学院(BSIO)的教育和职业相关目标是：(1)激发学生和本科生对癌症研究和科学事业的热情，(2)以联合的方式在翻译癌症研究方面教育基础科学家和(未来的)临床医生(目标是他们“说同样的语言”)，(3)向基础科学家指出临床表现和肿瘤学中最紧迫的问题，(4)使临床医生能够获得“R.R.NAT博士”。(博士)为了在基础科学家和临床医生之间建立共同语言，(5)提供与候选人个人职业概况相匹配的博士教育方案，(6)扩大研究生在博士期间的国际经验，(7)提供全面的指导概念，(8)确保从本科学习到第一个独立职位的“无缝”职业方案，(9)促进职业发展早期的关键过渡阶段，(10)在其他院校完成他们的第一个博士后职位(S)后，重新吸引最好的BSIO毕业生。结构目标是：(1)高效地指导研究生完成他们的博士项目，同时遵循最高质量标准，(2)促进在多机构大都市区的学习和工作，(3)扩大和加强现有的癌症研究结构。

项目成果

The transcription factor STAT5 catalyzes Mannich ligation reactions yielding inhibitors of leukemic cell proliferation

• DOI: 10.1038/s41467-018-07923-2
• 发表时间: 2019-01
• 期刊: Nature Communications
• 影响因子: 16.6
• 作者: Ee Lin Wong;Eric Nawrotzky;Christoph Arkona;Boo Geun Kim;Samuel Beligny;Xinning Wang;Stefan Wagner;M. Lisurek;D. Carstanjen;J. Rademann

Non-canonical HIF-1 stabilization contributes to intestinal tumorigenesis

• DOI: 10.1038/s41388-019-0816-4
• 发表时间: 2019-07-11
• 期刊: ONCOGENE
• 影响因子: 8
• 作者: Rohwer, Nadine;Jumpertz, Sandra;Cramer, Thorsten
• 通讯作者: Cramer, Thorsten

Temporal Splicing Switches in Elements of the TNF-Pathway Identified by Computational Analysis of Transcriptome Data for Human Cell Lines

• DOI: 10.3390/ijms20051182
• 发表时间: 2019-03-01
• 期刊: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
• 影响因子: 5.6
• 作者: Genov, Nikolai;Basti, Alireza;Relogio, Angela
• 通讯作者: Relogio, Angela

Cell type-dependent differential activation of ERK by oncogenic KRAS in colon cancer and intestinal epithelium

• DOI: 10.1038/s41467-019-10954-y
• 发表时间: 2019-07-02
• 期刊: NATURE COMMUNICATIONS
• 影响因子: 16.6
• 作者: Brandt, Raphael;Sell, Thomas;Morkel, Markus
• 通讯作者: Morkel, Markus

Epigenetic regulation of Amphiregulin and Epiregulin in colorectal cancer

• DOI: 10.1002/ijc.31892
• 发表时间: 2019-02-01
• 期刊: INTERNATIONAL JOURNAL OF CANCER
• 影响因子: 6.4
• 作者: Bormann, Felix;Stinzing, Sebastian;Sers, Christine
• 通讯作者: Sers, Christine