SBIR Phase I: New Plant Based Benign Actives for Sun screen and Cosmetics Applications

SBIR 第一阶段：用于防晒霜和化妆品应用的新型植物性良性活性物质

• 批准号: 0945799
• 负责人: Namita Deo
• 金额: --
• 依托单位: Nature's Secret Solutions Inc.
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-01-01 至 2010-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0945799&HistoricalAwards=false
• 关键词: SBIR; Phase; New; Plant; Based

This Small Business Innovation Research Phase I project will demonstrate the feasibility of plant-derived actives for sunscreen and other cosmetic applications. Recent research has raised concerns that the chemicals used in sunscreens and cosmetic products may be related to health problems, and their accumulation may also be an increasing threat to aquatic life. This research is focused on six plant extracts that have been shown to absorb UV light and scavenge free radicals 100 times better than currently available antioxidants. This feasibility study will include: i) isolation and identification of the active molecule(s) responsible for the beneficial properties; ii) investigation of the toxicity and stability of the molecule(s); and iii) identification of one or more active molecule(s) for use in all natural sunscreen/cosmetic products. The broader/commercial impact of this project, if successful, will be the availability of all natural sunscreen/cosmetics products devoid of negative side effects that synthetic analogs may bring. Commercial interest in effective natural sunscreen/cosmetic products have been validated with leading companies in cosmetics and personal care. Moreover, if successful, the increased scientific knowledge of natural extracts from this project may also find applications in nutraceuticals, and may contribute to cures and prevention of free radicals linked diseases. Industrial applications may also benefit from this work in applications such as UV stabilizer for polymers and pigments.

这个小型企业创新研究第一阶段项目将证明植物源活性物质用于防晒霜和其他化妆品应用的可行性。最近的研究引发了人们的担忧，即防晒霜和化妆品中使用的化学物质可能与健康问题有关，它们的积累也可能对水生生物构成越来越大的威胁。 这项研究的重点是六种植物提取物，这些植物提取物已被证明比目前可用的抗氧化剂更好地吸收紫外线和消除自由基100倍。该可行性研究将包括：i）分离和鉴定产生有益特性的活性分子; ii）研究分子的毒性和稳定性; iii）鉴定用于所有天然防晒/化妆品的一种或多种活性分子。 如果成功，该项目的更广泛/商业影响将是所有天然防晒霜/化妆品产品的可用性，而不会产生合成类似物可能带来的负面副作用。 化妆品和个人护理领域的领先公司已经证实了对有效天然防晒/化妆品的商业兴趣。 此外，如果成功，该项目增加的天然提取物科学知识也可能在营养保健品中找到应用，并可能有助于治疗和预防与自由基有关的疾病。 工业应用也可以从这项工作中受益，例如聚合物和颜料的紫外线稳定剂。