Fiber Lasers for Coherent Raman Microscopy

用于相干拉曼显微镜的光纤激光器

• 批准号: 0967949
• 负责人: Frank Wise
• 金额: $ 35.7万
• 依托单位: Cornell University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-05-01 至 2015-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0967949&HistoricalAwards=false
• 关键词: Fiber; Lasers; Coherent; Raman; Microscopy

0967949WiseCoherent anti-Stokes Raman scattering (CARS) microscopy is a sensitive and label-free nonlinear imaging technique that is attracting much interest. The technique requires an excitation source that provides two temporally-synchronized and wavelength-tunable picosecond light pulses. Existing sources of such pulses are complicated, expensive, and require trained operators, and these features create a major barrier to prospective users of CARS microscopy. A group from Cornell University will develop fiber-based light sources that promise to be integrated, stable, compact, and user-friendly. These will facilitate the expansion of CARS and related microscopy techniques beyond specialized research laboratories. The Cornell group will collaborate in the development with a group from Harvard University that is a leader in CARS microscopy. The generation of high-energy and wavelength-tunable picosecond pulses from an all-fiber source is a major challenge. New understanding of ultrafast nonlinear pulse propagation, and new ways to control ultrashort light pulses, will have to be developed in order to demonstrate the proposed capabilities. This will be converted into designs of short-pulse oscillators, amplifiers, and frequency-conversion stages. The development of such instruments is central to the fiber optics and ultrafast optics communities.

0967949 WiseCoherent anti-Stokes拉曼散射（汽车）显微术是一种灵敏且无标记的非线性成像技术，吸引了很多兴趣。该技术需要一个激发源，提供两个时间同步和波长可调的皮秒光脉冲。现有的这种脉冲源是复杂的，昂贵的，需要训练有素的操作员，这些功能创建一个主要的障碍，汽车显微镜的潜在用户。康奈尔大学的一个小组将开发基于光纤的光源，这些光源有望集成、稳定、紧凑和用户友好。这将促进汽车和相关显微镜技术在专业研究实验室之外的扩展。康奈尔大学的研究小组将与哈佛大学的一个研究小组合作开发，该研究小组是汽车显微镜的领导者。从全光纤光源中产生高能量和波长可调谐的皮秒脉冲是一个重大挑战。为了证明所提出的能力，必须开发对超快非线性脉冲传播的新理解和控制超短光脉冲的新方法。这将被转换为短脉冲振荡器，放大器和频率转换级的设计。这种仪器的开发是光纤和超快光学社区的核心。