SBIR Phase I: Flexible Plastic Packaging Without Estrogenic Activity (EA)

SBIR 第一阶段：不含雌激素活性 (EA) 的软塑料包装

• 批准号: 1013865
• 负责人: Daniel Klein
• 金额: --
• 依托单位: PlastiPure, Inc.
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2011-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1013865&HistoricalAwards=false
• 关键词: SBIR; Phase; Flexible; Plastic; Packaging

This Small Business Innovation Research (SBIR) Phase I project will confirm the feasibility of developing flexible packaging that does not leach chemicals having estrogenic or anti-estrogenic activity (EA), while maintaining all the fit-for-use properties of conventional flexible plastic packaging having EA. Hundreds of studies have shown that exogenous chemicals having EA can cause many adverse health effects (including reproductive dysfunctions, learning disabilities, birth defects, and increased rates of cancers). PlastiPure's data show that nearly all plastic products leach chemicals having easily detectable EA at concentrations having known adverse health effects. PlastiPure is developing proprietary materials and processes to fabricate EA-free flexible films and bags that are cost- and performance-competitive with conventional packaging having EA. This project is innovative because no other firm has shown that it is feasible to develop the polymer-based materials and processes needed to produce EA-free flexible films and bags for use in medical, food, and beverage packaging.The broader/commercial impacts of this research is the widespread commercialization of EA-free flexible film products. In the past few years, a rapid market switch from PC containing BPA-based plastics to BPA-free plastic products has shown that consumers apply market pressure to ensure that safer products are commercially available. Almost all BPA-free plastic products on the market today leach many chemicals having easily detectable EA, often at levels higher than the original BPA-based product. The funding of this NSF SBIR grant will help facilitate a comprehensive reduction of risks to public health and reduced environmental impact from chemicals having EA.

该小型企业创新研究（SBIR）第一阶段项目将确认开发不浸出具有雌激素或抗雌激素活性（EA）的化学品的软包装的可行性，同时保持具有EA的传统软塑料包装的所有适合使用的特性。 数百项研究表明，具有EA的外源性化学物质会导致许多不良健康影响（包括生殖功能障碍，学习障碍，出生缺陷和癌症发病率增加）。PlastiPure的数据显示，几乎所有的塑料产品都浸出了具有已知不良健康影响的浓度的易检测EA的化学品。 PlastiPure正在开发专有的材料和工艺，以制造不含EA的柔性薄膜和包装袋，这些薄膜和包装袋在成本和性能方面与含有EA的传统包装具有竞争力。该项目具有创新性，因为没有其他公司已经表明，它是可行的，以开发聚合物为基础的材料和工艺需要生产EA的柔性薄膜和袋用于医疗，食品和饮料包装。更广泛的/商业影响，这项研究是广泛的商业化EA的柔性薄膜产品。 在过去的几年里，从含有BPA的塑料到不含BPA的塑料产品的快速市场转变表明，消费者施加市场压力，以确保更安全的产品在市场上可获得。目前市场上几乎所有不含BPA的塑料产品都会浸出许多具有容易检测到的EA的化学品，其水平通常高于原始的BPA产品。NSF SBIR赠款的资金将有助于全面降低对公共健康的风险，并减少具有EA的化学品对环境的影响。