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Bridging the gap between eco-immunology and disease ecology: Symposium in Salt Lake City, Utah, January 3-7, 2011

Bridging the gap between eco-immunology and disease ecology: Symposium in Salt Lake City, Utah, January 3-7, 2011
弥合生态免疫学和疾病生态学之间的差距:2011 年 1 月 3-7 日在犹他州盐湖城举行的研讨会
批准号:
1042525
负责人:
Susannah French
金额:
$1.68万
依托单位:
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
2010
资助国家:
美国
项目状态:
已结题
起止时间:
2010-08-01 至 2011-07-31

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中文摘要
翻译
在综合与比较生物学学会年会上的这次研讨会将汇集在生态免疫学和疾病生态学领域工作的杰出研究人员,并提供一个论坛来审查各自子领域的研究。它将通过哲学和实证研究方法的讨论促进跨领域的合作,并就如何最好地利用当前技术来解决共同问题产生想法。抗病性是病原体动力学的一个功能,包括流行和毒力(疾病生态学),但也受到个体内部生理状态的驱动,包括宿主免疫功能(生态免疫学)。尽管这两个学科之间存在着相互联系,但大多数研究都只关注一个层面的分析,要么是最终的(寄生虫的进化和生态学及其对生活史的影响),要么是近似的(环境变量如何影响免疫反应)。然而,生态和进化因素对疾病易感性的影响不仅受到疾病及其载体的环境变化的影响,而且还受到宿主免疫功能差异的影响,这些差异改变了个体对疾病的易感性。研讨会的目标是批判性地回顾生态免疫学和疾病生态学学科的最新进展,并将近端和最终的观点整合到一个共同的理论框架中。
英文摘要
This symposium at the annual meeting of the Society for Integrative and Comparative Biology will bring together prominent researchers working in the areas of eco-immunology and disease ecology and to provide a forum to review research in their respective subfields. It will foster collaborations across fields through the discussion of philosophical and empirical research approaches, and generate ideas on how to best utilize current technologies to address the common questions. Disease resistance is a function of pathogen dynamics including prevalence and virulence (disease ecology), but is also driven by the internal physiological state of an individual, including host immune function (eco-immunology). Despite the interconnectedness between the two disciplines the majority of research has focused on only one level of analysis, either ultimate (evolution and ecology of parasites and their effects on life histories) or a proximate (how environmental variables affect immune responses). However, the effects of ecological and evolutionary factors on susceptibility to disease are driven not only by environmental variation in diseases and their vectors but also by differences in host immune function that alters disease susceptibility across individuals. The goal of the symposium is to critically review recent advances in the disciplines of eco-immunology and disease ecology, and to integrate both the proximate and ultimate perspectives into a common theoretical framework.
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