Collaborative Research: Causes and Consequences of Signal Evolution

马丁斯为IOS-1052247提案提供了摘要，多个性状之间的紧密整合可能会受到激素的影响，激素具有广泛的影响。这种整合了一系列相关性状的机制可能会潜在地限制性状的进一步进化，限制可能发生的变化。该项目将通过分析相关性状组背后的生理机制，详细说明如何将相关性状组“拉开”。该项目将研究蜥蜴属中12个密切相关的物种，在这些物种中，有一种特定的新奇特征有重复的起源。该项目将研究视觉和化学交流共同进化的生理和遗传机制，评估与信号产生和信号接收有关的特征。当研究物种密切相关时，PI还将开发必要的统计方法来分析相关性状的数据。由此产生的能够进行这种统计分析的软件将在网上免费提供，供其他研究人员使用。有各种各样的更广泛的影响。首先，本科生和研究生将接受培训，他们将与生物化学、分子生物学、神经生理学、动物行为学、进化生物学和生物统计学的研究人员合作。其次，这笔资金将通过在美国不同学科和机构的研究人员之间以及许多研究物种发生在墨西哥的研究人员之间建立合作，来加强研究和教育的基础设施。最后，私人投资机构将通过以下方式增进公众对科学和技术的了解：1)与印第安纳州的两个科学博物馆合作，根据资助的研究成果建立展示；2)通过现有的在线数据库服务(Ethosource)提供数据；3)将研究成果与私人投资机构与当地K-12科学教师建立的持续外展活动联系起来，以协助发展与项目所涉及的科学主题有关的教学单位。

Martins LAY ABSTRACT for proposal IOS- 1052247 Tight integration among multiple traits can be influenced by hormones, which have wide-ranging effects. Such mechanisms that integrate sets of correlated traits can potentially constrain further evolution of traits, limiting changes that can occur. The project will detail how sets of correlated traits may be "pulled apart" by analyzing physiological mechanisms underlying suites of correlated characters. The project will study twelve closely related species in a genus of lizards in which there are repeated origins of a specific novel trait. The project will study physiological and genetic mechanisms underlying the coevolution of visual and chemical communication, assessing traits involved in signal production and signal reception. The PIs will also develop statistical methods needed to analyze data on correlated traits when the study species are closely related. The resulting software enabling such statistical analyses will be made freely available online for use by other researchers. There are diverse broader impacts. First, undergraduate and graduate student will be trained and they will collaborate with researchers in biochemistry, molecular biology, neurophysiology, animal behavior, evolutionary biology, and biostatistics. Second, the funding will enhance infrastructure for research and education by establishing collaborations between researchers in different disciplines and institutions within the US, and also in Mexico where many of the study species occur. Finally, the PIs will enhance scientific and technological understanding by the public by 1) collaborating with two Indiana science museums to establish displays based on the funded research; 2) making data available by means of an existing online database service (Ethosource); and 3) connecting research outcomes with ongoing outreach activities that the PIs have established with local K-12 science teachers to assist in developing teaching units related to the science topics involved in the project.