Acqusition of Partcle Sizer

收购粒度分析仪

• 批准号: 1061200
• 负责人: Marek Romanowski
• 金额: $ 2万
• 依托单位: University of Arizona
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-10-01 至 2011-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1061200&HistoricalAwards=false
• 关键词: Acqusition; Partcle; Sizer

PI: Marek Romanowski Proposal No. 1061200Acquisition of Particle SizerAbstractThe main goal of this proposal is to acquire a particle sizer appropriate for determination of size distributions of various particles prepared on the nanometer scale for experimental applications in medical diagnostics and therapy. The main thrust of the research work in this laboratory has been to develop engineered structures in the nanometer size range for medical diagnosis and intervention. Not only is this size range compatible with molecular targeting and cellular delivery, but it also allows for the manipulation of materials with unprecedented control of their optical and electronic properties, specifically tailored for biomedical applications. Examples generated in this laboratory include biodegradable plasmon resonant nanoshells and spectrally controlled content release. Data generated by this particle sizer will help the process of manipulation of optical and biological properties of multifunctional nanostructures developed by this investigator. In addition, this proposal addresses the need of several researchers at this location who require characterization of materials on the nanometer scale. Such characterizations have become especially important in research programs concerned with molecular imaging and targeted therapy, colloidal chemistry, and conformation of proteins, pursued by the faculty associated with the Department of Biomedical Engineering at the University of Arizona. Therefore, one of the aims of this proposal is to provide access to this instrumental capability to researchers pursuing related research directions at this location. Finally, an integral part of this proposal is to provide research and educational opportunities to students with interest in engineering materials on the nanometer scale, and to enhance educational curriculum in the areas of photonics, material science, and nanomedicine.

主要研究者：MarekRomanowski建议No.1061200获得粒度仪摘要该建议的主要目标是获得一种粒度仪，该粒度仪适用于测定在纳米尺度上制备的各种颗粒的粒度分布，用于医学诊断和治疗的实验应用。 该实验室研究工作的主要方向是开发纳米尺寸范围内的工程结构，用于医疗诊断和干预。该尺寸范围不仅与分子靶向和细胞递送相容，而且还允许对材料进行操作，对其光学和电子特性进行前所未有的控制，特别是针对生物医学应用而定制。 该实验室产生的例子包括可生物降解的等离子体共振纳米壳和光谱控制的内容物释放。 该粒度仪产生的数据将有助于本研究人员开发的多功能纳米结构的光学和生物学特性的操作过程。 此外，该提案还满足了该地点的几位研究人员的需要，他们需要在纳米尺度上表征材料。 这种表征在与分子成像和靶向治疗、胶体化学和蛋白质构象有关的研究计划中变得特别重要，这些研究计划由亚利桑那大学生物医学工程系的教师进行。 因此，本提案的目的之一是为在该地点从事相关研究方向的研究人员提供利用这一工具能力的机会。最后，本提案的一个组成部分是为对纳米级工程材料感兴趣的学生提供研究和教育机会，并加强光子学，材料科学和纳米医学领域的教育课程。