Workshop: Phenomes - Beyond Genomes; April 1-2, 2011; St. Louis, MO

研讨会：现象组 - 超越基因组；

• 批准号: 1129780
• 负责人: Robert Last
• 金额: $ 2.14万
• 依托单位: Michigan State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-03-15 至 2012-02-29
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1129780&HistoricalAwards=false
• 关键词: Workshop; Phenomes; Beyond; Genomes; April

Intellectual Merit: A two-day workshop to be held on April 1 and 2, 2011 in St. Louis, Missouri will bring 20-25 invited scholars from diverse fields to address how investments in genome resource development (genome sequencing and annotation, genetic and physical mapping, gene expression datasets, mutant collections, proteomic and various other "omics") can be leveraged and further developed in the emerging field of "Phenomics", the study of phenotypes. Four keynote speakers will deliver presentations on the broad topic of Phenomics to set the tone of the meeting and catalyze discussion. All participants will have ample opportunity for conversation on key questions and issues in brainstorming sessions immediately following each keynote talk, through breakout groups specifically oriented to the identification of grand challenges, and through participation in the production of a White Paper as a recorded, published outcome of the workshop. The fundamental purpose of the workshop is to encourage substantive and timely cross-disciplinary dialog such that new formulations of priorities for Federal funding may emerge. The workshop will include participation from researchers using "top-down" (phenotype to genotype) and "bottom-up" (genotype to phenotype) approaches. These scientists represent areas of research ranging from relatively simple single species studies through complex multi-organism systems. Participants were invited from a diverse set of fields using a range of systems and organisms, including plant breeding, microbiololgy, metagenomics, bioinformatics and systems biology. Broader Impacts: The White Paper from the workshop will outline grand challenges that lie ahead in integrating phenotypic with genomic information in a tractable and productive manner. The Paper will articulate what benefits could arise from increased integration and coordination; identify current gaps in knowledge, infrastructure, and disciplinary interactions; and recommend directions in research and funding. Clarification and enumeration of short- and long-term goals will be of benefit to researchers and government agencies spanning a range of interests and expertise from computer science to agriculture. It is expected that the White Paper will seed cross-disciplinary dialog and collaborations to establish Phenomics as a vibrant discipline encompassing the full range of genotype by environment interactions that underpin phenotypic variation. Additionally, the workshop will include scholars from diverse career stages, institutional types, geographical locations, gender and ethnic backgrounds.

智力优势：为期两天的研讨会将于2011年4月1日至2日在密苏里州圣路易斯举行，届时将邀请20-25位来自不同领域的受邀学者，讨论如何在基因组资源开发（基因组测序和注释、遗传和物理制图、基因表达数据集、突变体收集、蛋白质组学和各种其他“组学”）方面的投资可以在“表型组学”这一新兴领域中得到利用和进一步发展。四位主讲人将就表型组学的广泛主题发表演讲，以确定会议的基调并促进讨论。所有与会者都将有充分的机会在每次主题演讲之后的头脑风暴会议上就关键问题和议题进行对话，通过专门针对重大挑战的分组讨论，并通过参与制作白皮书作为研讨会成果的记录和出版。讲习班的根本目的是鼓励实质性和及时的跨学科对话，以便可能出现联邦资金优先次序的新方案。研讨会将包括使用“自上而下”（表现型到基因型）和“自下而上”（基因型到表现型）方法的研究人员。这些科学家代表了从相对简单的单一物种研究到复杂的多生物系统的研究领域。与会者被邀请来自使用一系列系统和生物体的不同领域，包括植物育种、微生物学、宏基因组学、生物信息学和系统生物学。更广泛的影响：研讨会的白皮书将概述以可处理和有效的方式整合表型与基因组信息所面临的重大挑战。该文件将阐明加强一体化和协调可能带来的好处；确定当前在知识、基础设施和学科互动方面的差距；并建议研究和资助的方向。澄清和列举短期和长期目标将有利于跨越从计算机科学到农业的一系列兴趣和专业知识的研究人员和政府机构。预计白皮书将为跨学科对话和合作提供种子，以建立表型组学作为一个充满活力的学科，涵盖了支持表型变异的环境相互作用的基因型的全部范围。此外，讲习班将包括来自不同职业阶段、机构类型、地理位置、性别和种族背景的学者。