CAREER: Synthesis and Fundamental Organometallic Reactivity of Low-Valent Uranium Alkyls

职业：低价烷基铀的合成和基本有机金属反应性

• 批准号: 1149875
• 负责人: Suzanne Bart
• 金额: $ 50万
• 依托单位: Purdue University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-09-01 至 2017-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1149875&HistoricalAwards=false
• 关键词: CAREER; Synthesis; Fundamental; Organometallic; Reactivity

With this CAREER Award, the Chemistry Synthesis program is supporting the research of Professor Suzanne Bart at Purdue University. In this project, Professor Bart will focus on the synthesis, characterization, and reactivity of reduced uranium complexes for small molecule activation. The planned research will test the hypothesis that low-valent uranium alkyls are useful synthons for elusive uranium targets. Experiments will be carried out to 1) obtain a family of uranium(III) alkyls with a variety of ancillary ligands, 2) understand under what conditions uranium can undergo two electron processes, similar to late transition metals, including reductive elimination, oxidative addition, and migratory insertion, 3) explore the utility of uranium alkyls for multiple bond formation. The planned research includes synthetic methods, spectroscopic analysis, and computational approaches to fully understand the reactivity of these compounds.In terms of the educational plan, Professor Suzanne Bart will continue and expand her initiative to increase the population of women among college age science majors with her ChemTeens conference (formerly "High School Day on Campus for Girls"). Through this program, junior and senior female students are invited to interact with leading female faculty in the chemical sciences at Purdue to learn about careers, college majors, and the benefits and challenges of a career in the sciences. At this event, participants also make connections with current undergraduate and graduate students who can serve as mentors and take the intimidation out of a major in science as the participants begin their college careers. Professor Bart will also participate in a program aimed at high school teachers in Indiana. Through this program, the high school teachers could perform and videotape in Professor Bart's laboratory those demonstrations not possible in their own classrooms. These demonstrations help to highlight the importance of rare earth and actinide elements.

有了这个职业奖，化学合成计划正在支持普渡大学苏珊娜·巴特教授的研究。 在这个项目中，巴特教授将专注于小分子活化还原铀络合物的合成，表征和反应性。 计划中的研究将检验一种假设，即低价烷基铀对难以捉摸的铀目标是有用的质子。 实验将进行1）获得一个家庭的铀（III）烷基与各种辅助配体，2）了解在什么条件下铀可以经历两个电子的过程，类似于后过渡金属，包括还原消除，氧化加成，和迁移插入，3）探索铀烷基多键形成的效用。计划中的研究包括合成方法、光谱分析和计算方法，以充分了解这些化合物的反应性。在教育计划方面，Suzanne Bart教授将继续并扩大她的倡议，通过她的ChemTeens会议（原“女孩校园高中日”）增加大学年龄科学专业的女性人口。通过这个项目，大三和大四的女学生被邀请与普渡大学化学科学领域的领先女性教师互动，了解职业，大学专业以及科学职业的好处和挑战。在这次活动中，参与者还与当前的本科生和研究生建立联系，他们可以担任导师，并在参与者开始大学生涯时消除科学专业的恐吓。 巴特教授还将参加一个针对印第安纳州高中教师的项目。 通过这个项目，高中教师可以在巴特教授的实验室里表演和录像那些在他们自己的教室里不可能的演示。 这些演示有助于突出稀土和锕系元素的重要性。