CAREER: Molecular Reorganization of Simple Substrates into Complex Products

职业：将简单底物分子重组为复杂产品

• 批准号: 1150875
• 负责人: Uttam Tambar
• 金额: $ 55万
• 依托单位: University of Texas Southwestern Medical Center
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-09-01 至 2017-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1150875&HistoricalAwards=false
• 关键词: CAREER; Molecular; Reorganization; Simple; Substrates

With this CAREER award, the Chemistry Synthesis program is supporting the research of Professor Uttam K. Tambar of the University of Texas Southwestern Medical Center. Professor Tambar will develop novel molecular reorganization processes, wherein a simple starting material selectively rearranges into a more complex and more valuable product. Molecular rearrangements have pervaded organic chemistry for decades. In fact, some of the most fundamental principles of chemical reactivity were elucidated in the context of molecular rearrangements. Professor Tambar is interested in studying areas of molecular reorganization that are underdeveloped. His group will develop selective rearrangements that will facilitate the synthesis of complex molecules, including polycyclic natural products. In the process of developing these new transformations, Professor Tambar's group will focus on elucidating new concepts in chemical reactivity.Professor Tambar will also initiate new educational activities that will integrate his research goals with his commitment to educate the broader community of chemistry's role in improving our quality of life. These initiatives include introducing elementary school students to chemical synthesis, improving Chemical Safety Training for graduate students and postdoctoral scientists at his university, and organizing Science Cafés for the general public of Dallas-Fort Worth area.

有了这个职业奖，化学合成计划是支持教授Uttam K。德克萨斯大学西南医学中心的Tambar博士说。 Tambar教授将开发新的分子重组过程，其中简单的起始材料选择性地重新排列成更复杂，更有价值的产品。 分子重排在有机化学中已经存在了几十年。 事实上，化学反应性的一些最基本的原理是在分子重排的背景下阐明的。 Tambar教授对研究分子重组的未开发领域感兴趣。 他的团队将开发选择性重排，以促进复杂分子的合成，包括多环天然产物。 Tambar教授的团队将致力于阐明化学反应性的新概念，并将开展新的教育活动，将他的研究目标与他致力于教育更广泛的社区化学在改善我们生活质量方面的作用相结合。 这些举措包括向小学生介绍化学合成，改善他所在大学研究生和博士后科学家的化学品安全培训，并为达拉斯-沃思堡地区的公众组织科学咖啡馆。