Catalyzing New International Collaborations: 3D Morphometric and Biomechanical Analyses of the Human Lower Limb
促进新的国际合作:人类下肢的 3D 形态测量和生物力学分析
基本信息
- 批准号:1158603
- 负责人:
- 金额:$ 6.43万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:2012
- 资助国家:美国
- 起止时间:2012-07-01 至 2014-06-30
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
This award provides funding to initiate a new international collaboration between researchers at Pennsylvania State University and three European Universities - the University of Vienna, the University of Cambridge, and the University of Bologna. The goal of the project is to develop new methods for analyzing the three-dimensional (3D) structure and associated functions of human limb bones. The project will bring together experts in analyses of skeletal form and morphometrics from the Universities of Vienna and Bologna and experts in skeletal biomechanics from Penn State and the University of Cambridge. The primary goal is to develop new methods for integrative analyses of the bones of the lower limb in humans. These methods will be developed within the context of several specific questions relating to the morphology of the human lower limb and will be addressed using existing 3D high-resolution computed tomography (HRCT) data and new HRCT data collected at Penn State and Vienna. The award will support planning visits, new data collection, and US graduate student training. The data produced will be of significant importance to a broad range of anthropological, paleontological, and archaeological studies.Intellectual Merit. The expectations of this study are to develop a new understanding of the significance of variation in whole diaphysis cortical bone structure and whole bone shape. In so doing, this collaboration will illuminate the relative importance and usefulness of bone functional adaptation in shaping the elements of the human lower limb. The simultaneous analysis of bone shape and mechanical adaptation is expected to be a powerful tool to produce a broader understanding of skeletal functional adaptation.Broader Impacts. This study enhances the infrastructure of research in physical anthropology by merging methodological approaches in morphological analysis to gain an understanding of skeletal variation and functional adaptation for use in paleontological and bioarchaeological behavioral reconstructions. This project will catalyze collaboration among researchers from the United States, Austria, Italy, and England, each of whom has specific expertise in 2D and 3D morphometric and biomechanical techniques. This project will enhance the educational experience of several U.S. students at both the graduate and undergraduate levels including one female minority graduate student at Penn State. Data, methods, and theoretical concepts will also be incorporated into current undergraduate courses taught by the PI at Penn State.
该奖项为宾夕法尼亚州立大学和三所欧洲大学(维也纳大学、剑桥大学和博洛尼亚大学)的研究人员之间开展新的国际合作提供资金。该项目的目标是开发分析人体四肢骨骼三维(3D)结构和相关功能的新方法。该项目将汇集来自维也纳大学和博洛尼亚大学的骨骼形态和形态计量学分析专家以及来自宾夕法尼亚州立大学和剑桥大学的骨骼生物力学专家。主要目标是开发新的方法,用于人体下肢骨骼的综合分析。这些方法将在与人类下肢形态有关的几个具体问题的背景下开发,并将使用现有的3D高分辨率计算机断层扫描(HRCT)数据和在宾夕法尼亚州立大学和维也纳收集的新HRCT数据进行解决。该奖项将支持规划访问,新数据收集和美国研究生培训。所产生的数据将对广泛的人类学、古生物学和考古学研究具有重要意义。本研究的期望是对整个骨干、皮质骨结构和整个骨形状的变化的意义有一个新的认识。在这样做的过程中,这种合作将阐明骨功能适应在塑造人类下肢元素中的相对重要性和有用性。骨形状和机械适应的同时分析有望成为一个强大的工具,以产生更广泛的理解骨骼功能的适应。本研究通过合并形态学分析的方法论方法来增强体质人类学研究的基础设施,以了解骨骼变异和功能适应,用于古生物学和生物考古学行为重建。该项目将促进来自美国,奥地利,意大利和英国的研究人员之间的合作,他们每个人都在2D和3D形态测量和生物力学技术方面具有特定的专业知识。这个项目将提高几个美国学生在研究生和本科阶段的教育经验,其中包括一名宾夕法尼亚州立大学的少数民族女研究生。数据,方法和理论概念也将被纳入由PI在宾夕法尼亚州立大学教授的当前本科课程。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Timothy Ryan其他文献
Structural insights into the modes of relaxin-binding and tethered-agonist activation of RXFP1 and RXFP2
RXFP1 和 RXFP2 的松弛素结合和系留激动剂激活模式的结构见解
- DOI:
10.1101/2021.06.06.446989 - 发表时间:
2021 - 期刊:
- 影响因子:0
- 作者:
Ashish Sethi;Shoni Bruell;Timothy Ryan;Fei Yan;Mohammad Tanipour;Yee;C. Draper;Y. Khandokar;R. Metcalfe;M. Griffin;D. Scott;M. A. Hossain;E. Petrie;R. Bathgate;P. Gooley - 通讯作者:
P. Gooley
Incidence of type 2 diabetes, cardiovascular disease and chronic kidney disease in patients with multiple sclerosis initiating disease-modifying therapies: Retrospective cohort study using a frequentist model averaging statistical framework
开始疾病修饰治疗的多发性硬化症患者 2 型糖尿病、心血管疾病和慢性肾脏病的发病率:使用频率模型平均统计框架的回顾性队列研究
- DOI:
- 发表时间:
2024 - 期刊:
- 影响因子:3.7
- 作者:
Alan J. M. Brnabic;Sarah E. Curtis;Joseph A Johnston;Albert Lo;Anthony J. Zagar;Ilya Lipkovich;Zbigniew Kadziola;Megan H. Murray;Timothy Ryan - 通讯作者:
Timothy Ryan
Morphometric analysis of the hominin talus: Evolutionary and functional implications.
人类距骨的形态测量分析:进化和功能的影响。
- DOI:
10.1016/j.jhevol.2020.102747 - 发表时间:
2020 - 期刊:
- 影响因子:3.2
- 作者:
Rita Sorrentino;K. Carlson;E. Bortolini;Caterina Minghetti;F. Feletti;Luca Fiorenza;Stephen R. Frost;T. Jashashvili;W. Parr;C. Shaw;A. Su;K. Turley;S. Wroe;Timothy Ryan;M. G. Belcastro;S. Benazzi - 通讯作者:
S. Benazzi
IMPROVEMENT IN SEVERE KIDNEY DYSFUNCTION AFTER IMPLANTATION OF CONTINUOUS-FLOW LEFT VENTRICULAR ASSIST DEVICES
- DOI:
10.1016/s0735-1097(13)60780-9 - 发表时间:
2013-03-12 - 期刊:
- 影响因子:
- 作者:
Shikhar Saxena;John Um;Ioana Dumitru;Brock Cookman;Samantha Pilmaier;Timothy Ryan;Shannon Yannone;Michael Moulton;Brian Lowes;Eugenia Raichlin - 通讯作者:
Eugenia Raichlin
Impact of INTERMACS and Composite Preoperative Mortality Risk Score Stratification on Survival in Patients Receiving Heart Mate II LVAD as Bridge to Transplantation
- DOI:
10.1016/j.cardfail.2010.06.182 - 发表时间:
2010-08-01 - 期刊:
- 影响因子:
- 作者:
Nicholas Haglund;Eugenia Raichlin;Timothy Ryan;John Um;Ioana Dumitru - 通讯作者:
Ioana Dumitru
Timothy Ryan的其他文献
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{{ truncateString('Timothy Ryan', 18)}}的其他基金
Doctoral Dissertation Research: Variation in human bone structure across subsistence strategy transitions
博士论文研究:人类骨骼结构在生存策略转变过程中的变化
- 批准号:
1847806 - 财政年份:2019
- 资助金额:
$ 6.43万 - 项目类别:
Standard Grant
ABI Development: Collaborative Research: The first open access digital archive for high fidelity 3D data on morphological phenomes
ABI 开发:协作研究:第一个开放存取数字档案,用于形态学现象的高保真 3D 数据
- 批准号:
1661132 - 财政年份:2017
- 资助金额:
$ 6.43万 - 项目类别:
Continuing Grant
SBE-RCUK: Collaborative Research: The effects of mobility and physical activity on human postcranial skeletal variation
SBE-RCUK:合作研究:活动性和体力活动对人类颅后骨骼变异的影响
- 批准号:
1719187 - 财政年份:2017
- 资助金额:
$ 6.43万 - 项目类别:
Continuing Grant
Collaborative Research: Pliocene Geology, Geochronology, and Paleontology of Woranso-Mille, Ethiopia
合作研究:埃塞俄比亚沃兰索米勒的上新世地质学、年代学和古生物学
- 批准号:
1124713 - 财政年份:2011
- 资助金额:
$ 6.43万 - 项目类别:
Standard Grant
Collaborative Research: Trabecular bone ontogeny and locomotor development in humans and non-human primates
合作研究:人类和非人类灵长类动物的骨小梁个体发育和运动发育
- 批准号:
1028904 - 财政年份:2010
- 资助金额:
$ 6.43万 - 项目类别:
Continuing Grant
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