DISSERTATION RESEARCH: The evolution of selenium hyperaccumulation in Stanleya (Brassicaceae)
论文研究:斯坦利亚(十字花科)硒超积累的演变
基本信息
- 批准号:1210752
- 负责人:
- 金额:$ 1.49万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:2012
- 资助国家:美国
- 起止时间:2012-05-01 至 2014-04-30
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Selenium is atomically similar to sulfur and because of this relationship it can replace sulfur in proteins. Accidental incorporation of selenium can cause disease and even death in humans, livestock and wildlife. Yet selenium is also an essential micronutrient for many animals, prokaryotes and algae, though there is no known function of selenium in land plants. There are four plant genera with species recognized as selenium hyperaccumulators (accumulating 0.1% dry weight selenium), including Stanleya (prince's plume; Brassicaceae) in the western United States. Stanleya includes seven species, one of which (Stanleya pinnata) is a known selenium hyperaccumulator. The goal of this project is to infer the process of diversification of selenium accumulation, tolerance, localization and chemical form in the context of intraspecific relationships within Stanleya to better understand which DNA changes caused these physiological changes. By understanding which DNA changes gave rise to selenium accumulation and tolerance we can improve crops for both phytoremediation (environmental clean-up using plants) and biofortification. Selenium deficiency is estimated to cause $545 million in losses to livestock producers every year. Stanleya pinnata metabolizes selenium into a healthy anti-carcinogenic form, and understanding this physiological pathway may lead to improved crops for both humans and livestock.
硒在原子上与硫相似,由于这种关系,它可以取代蛋白质中的硫。硒的意外掺入可导致人类、牲畜和野生动物的疾病甚至死亡。然而,硒也是许多动物、原核生物和藻类的必需微量营养素,尽管硒在陆地植物中的功能尚不清楚。有四种植物属的物种被认为是高硒(积累0.1%干重硒),包括美国西部的Stanleya(王子羽;菊科)。Stanleya包括7种,其中一种(Stanleya pinnata)是已知的硒超富集植物。该项目的目标是推断Stanleya内种内关系背景下硒积累,耐受性,定位和化学形式多样化的过程,以更好地了解哪些DNA变化导致这些生理变化。通过了解哪些DNA变化引起了硒的积累和耐受性,我们可以改善作物的植物修复(使用植物清理环境)和生物强化。据估计,硒缺乏每年给畜牧业生产者造成5.45亿美元的损失。Stanleya pinnata将硒代谢成健康的抗癌形式,了解这一生理途径可能会导致人类和牲畜的作物改良。
项目成果
期刊论文数量(0)
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专利数量(0)
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Mark Simmons其他文献
The effect of gas turbine lubricant base oil molecular structure on friction
- DOI:
10.1016/j.triboint.2019.106052 - 发表时间:
2020-06-01 - 期刊:
- 影响因子:
- 作者:
Jake Airey;Matthew Spencer;Richard Greenwood;Mark Simmons - 通讯作者:
Mark Simmons
Teaching arms and screens for microscope and fibreoptic nasendoscope: are they effective teaching devices and are we utilising them?
- DOI:
10.1007/s00405-009-1063-z - 发表时间:
2009-08-19 - 期刊:
- 影响因子:2.200
- 作者:
Eu Chin Ho;Lucy Jane Baker;Hugh Savage;Mark Simmons - 通讯作者:
Mark Simmons
Regulation of the trans sarcolemmal calcium current in isolated cardiac myocytes by acetylcholine and cyclic GMP
乙酰胆碱和环鸟苷酸对离体心肌细胞跨肌膜钙电流的调节
- DOI:
- 发表时间:
2023 - 期刊:
- 影响因子:0
- 作者:
H. C. Hartzell;Mark Simmons;R. Fischmeister - 通讯作者:
R. Fischmeister
Full-thickness skin grafts and perichondrial cutaneous grafts following surgical removal of cutaneous neoplasms of the head and neck
- DOI:
10.1007/s00405-010-1210-6 - 发表时间:
2010-02-18 - 期刊:
- 影响因子:2.200
- 作者:
Paul van der Eerden;Mark Simmons;Karel Zuur;Harm van Tinteren;Hade Vuyk - 通讯作者:
Hade Vuyk
Ear microbiology reports: a need for better communication with the microbiologists
- DOI:
10.1007/s00405-009-1082-9 - 发表时间:
2009-09-16 - 期刊:
- 影响因子:2.200
- 作者:
Eu Chin Ho;Gaurav Chawdhary;Aaisha Khan;Stephen G. Jones;Mark Simmons - 通讯作者:
Mark Simmons
Mark Simmons的其他文献
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{{ truncateString('Mark Simmons', 18)}}的其他基金
Embedding Manufacturing Development into Formulation Research (EMFormR)
将制造开发嵌入配方研究 (EMFormR)
- 批准号:
EP/L505766/1 - 财政年份:2014
- 资助金额:
$ 1.49万 - 项目类别:
Research Grant
DISSERTATION RESEARCH: Quantifying genetic and ecological variation to delimit species in Hawaiian Pritchardia (Palmae)
论文研究:量化遗传和生态变异以界定夏威夷普里查迪亚(棕榈)物种
- 批准号:
1010731 - 财政年份:2010
- 资助金额:
$ 1.49万 - 项目类别:
Standard Grant
Phylogeny and diversification of the aril in the Celastraceae
卫矛科假种皮的系统发育和多样化
- 批准号:
0639792 - 财政年份:2007
- 资助金额:
$ 1.49万 - 项目类别:
Standard Grant
Cell Factories: A Matter of Life or Death
细胞工厂:生死攸关
- 批准号:
EP/E000843/1 - 财政年份:2006
- 资助金额:
$ 1.49万 - 项目类别:
Research Grant
Collaborative Research: Linked Databases and an Interactive Key for the Vascular Flora of the Southern Rocky Mountain Region
合作研究:落基山脉南部地区维管植物区系的链接数据库和交互式密钥
- 批准号:
0237240 - 财政年份:2003
- 资助金额:
$ 1.49万 - 项目类别:
Standard Grant
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Research on Quantum Field Theory without a Lagrangian Description
- 批准号:24ZR1403900
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Cell Research
- 批准号:31224802
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- 批准号:30824808
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- 批准号:10774081
- 批准年份:2007
- 资助金额:45.0 万元
- 项目类别:面上项目
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