MRI: Acquisition of an ABI genetic analyzer for Research and Research Training at a Predominately Undergraduate Institution
MRI:购买 ABI 基因分析仪,用于本科院校的研究和研究培训
基本信息
- 批准号:1229463
- 负责人:
- 金额:$ 6.45万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:2012
- 资助国家:美国
- 起止时间:2012-08-01 至 2015-07-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
The Applied Biosystems 310 Genetic Analyzer will provide researchers with instrumentation to promote and foster the advancement of individual and collaborative research opportunities in the dynamic and growing areas of genomics, molecular evolutionary biology and systematic, cell and molecular biology, microbiology, and forensic science at The University of Findlay. The genetic analyzer will provide opportunities to enhance the current research of faculty and undergraduate researchers, and provide exciting opportunities to develop and implement new research ideas and techniques possible only through advanced sequencing and fragment generation and analysis. Specific projects that will require extensive use of the genetic analyzer include investigations into: 1) evolutionary biology using sequence and fragment data, including phylogeography and population genetics, of amphibians and reptiles; 2) mutation frequencies and structural rearrangements of chromosomes; 3) the discovery and prevalence of Ranavirus in a natural preserve and a restored wetland in northern Ohio; 4) antibiotic resistance using bioflims in commercial and organic farms; and 5) in silico and in vitro Analysis of Protein Intrinsic Disorder. As a predominantly undergraduate institution, instrumentation, such as the requested Genetic Analyzer, is crucial in assisting us to integrate research into our curriculum where we train the next generation of scientists and foster faculty?s research interests.The broader impacts of the proposed activities for the faculty and undergraduate researchers at The University of Findlay, the scientific community, and society are on par with the goals of the NSF-MRI program and include: 1) providing access to shared scientific instrumentation for research and training of faculty and to the broader scientific community through training sessions; 2) developing interdisciplinary and collaborative research opportunities among researchers; 3) enhancing opportunities for basic research techniques (e.g., experimental design, molecular methodologies and techniques), as well as teaching, training, and learning related to modern sequencing techniques and fragment analysis; 4) disseminating novel research findings, methods, and training opportunities to the broader scientific research community through peer-reviewed publications in scientific journals and attendance and presentations at scientific meetings; 5) providing exceptional access and hands-on training using advanced instrumentation to undergraduate students, who encounter such equipment rarely or only upon study at the graduate level; 6) developing critical thinking and problem-solving skills, which augments the learning experiences for undergraduate students; and 7) offering outreach opportunities for area primary, middle, and secondary schools, as well as area college students, to learn basic sequencing techniques from research scientists in their field of interest.
Applied Biosystems 310遗传分析仪将为研究人员提供仪器,以促进和促进芬德利大学在基因组学,分子进化生物学和系统,细胞和分子生物学,微生物学和法医学等动态和不断增长的领域的个人和合作研究机会的进步。遗传分析仪将提供机会,以加强教师和本科生研究人员的当前研究,并提供令人兴奋的机会,开发和实施新的研究思路和技术可能只有通过先进的测序和片段生成和分析。需要广泛使用遗传分析仪的具体项目包括:1)使用序列和片段数据的进化生物学研究,包括两栖动物和爬行动物的种群地理学和种群遗传学; 2)染色体的突变频率和结构重排; 3)在北方俄亥俄州的自然保护区和恢复湿地中发现和流行Ranavirus; 4)在商业和有机农场中使用生物膜的抗生素抗性;和5)蛋白质内在紊乱的计算机和体外分析。 作为一个主要的本科院校,仪器,如要求的遗传分析仪,是至关重要的,在协助我们将研究纳入我们的课程,我们培养下一代科学家和培养教师?芬德雷大学的教师和本科生研究人员,科学界和社会的拟议活动的更广泛的影响与NSF-MRI计划的目标一致,包括:1)通过培训课程为教师和更广泛的科学界提供共享的科学仪器; 2)在研究人员之间发展跨学科和合作研究的机会; 3)增加基础研究技术的机会(例如,实验设计,分子方法和技术),以及与现代测序技术和片段分析相关的教学,培训和学习; 4)通过在科学期刊上发表同行评议的出版物以及出席和在科学会议上发表演讲,向更广泛的科学研究界传播新的研究成果,方法和培训机会; 5)为本科生提供使用先进仪器的特殊机会和实践培训,他们很少或只有在研究生阶段学习时才会遇到这种设备; 6)培养批判性思维和解决问题的技能,这增加了本科生的学习经验;以及7)为地区小学、初中和中学以及地区大学生提供外展机会,从他们感兴趣的领域的研究科学家那里学习基本的测序技术。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Philip Lucas其他文献
Highlights of the 22nd Annual Scientific Meeting of the Australasian Musculoskeletal Imaging Group [AMSIG] 2018, Gold Coast, Queensland, Australia
- DOI:
10.1007/s00256-018-3082-6 - 发表时间:
2018-10-13 - 期刊:
- 影响因子:2.200
- 作者:
Ryan Shulman;Timothy Dickson;Gregory Cowderoy;Philip Lucas;Morgan McMeniman - 通讯作者:
Morgan McMeniman
Highlights of the 23rd Annual Scientific Meeting of the Australasian Musculoskeletal Imaging Group (AMSIG) 2019, Queenstown, New Zealand
- DOI:
10.1007/s00256-019-03333-7 - 发表时间:
2019-11-15 - 期刊:
- 影响因子:2.200
- 作者:
Gregory Cowderoy;Philip Lucas;Timothy Dickson;Bill Breidahl;Anthony Doyle;Avneesh Chhabra;David Panicek;Graeme Anderson;Fiona McQueen;Katrina Glazebrook;Wayne McIlwraith;Julien Freitag;Ogonna Kenechi (Kenny) Nwawka;Alastair Eason;James Linklater;Paul Marks - 通讯作者:
Paul Marks
Philip Lucas的其他文献
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