I/UCRC: Looking beyond catastrophic brain injuries to mild traumatic brain injury -fundamental research to advance new frontiers in injury prevention

I/UCRC：从灾难性脑损伤到轻度创伤性脑损伤——推进损伤预防新领域的基础研究

• 批准号: 1230312
• 负责人: Flaura Winston
• 金额: $ 19.57万
• 依托单位: The Children's Hospital of Philadelphia
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-07-01 至 2014-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1230312&HistoricalAwards=false
• 关键词: UCRC; Looking; beyond; catastrophic; brain

Center for Child Injury Prevention Studies (CChIPS) Proposal # 1230312 Flaura Winston This proposal seeks funding for the Center for Child Injury Prevention Studies (CChIPS) located at the Children's Hospital of Philadelphia. Funding Requests for Fundamental Research are authorized by an NSF approved solicitation, NSF 11-570. The solicitation invites I/UCRCs to submit proposals for support of industry-defined fundamental research. Concussions (also known as mild traumatic brain injuries - mTBI) are not only the most common injury sustained by children in crashes but often lead to poor outcomes that affect a child's quality of life. Understanding the biomechanics of mTBI for children goes beyond automotive injury prevention and advances a CChIPS strategic goal of expansion into sports injury prevention. This Fundamental Research proposal addresses industrys need for data to drive safety innovation on preventing mTBI in children. The primary objectives in this proposed research are to: 1) validate the ability of helmet-based sensors to measure the head acceleration of a helmeted youth hockey player and 2) quantify the head biomechanics experienced by youth hockey players across a typical season and correlate these to measured neurocognitive deficits. By providing an in-depth understanding of injury mechanisms and injury metrics associated with concussion linked with medical data, this research will lead to new ATD (anthropometric test device), injury criteria and testing protocols. These new tools will fuel the cycle of product development for technology to prevent mTBI in children both for the automotive and sports equipment industries. The proposed work will contribute novel data relating engineering metrics to neurological and cognitive outcomes associated with head impacts to the pre-adolescent. This project also facilitates creation of an international site of CChIPS in Sweden and provides a platform for attracting new members from the sports injury prevention industry.

儿童伤害预防研究中心（CChIPS）提案# 1230312 Flaura Winston该提案为位于费城儿童医院的儿童伤害预防研究中心（CChIPS）寻求资金。基础研究的资金申请由NSF批准的征求授权，NSF 11-570。本次招标邀请I/ ucrc提交支持行业定义基础研究的提案。脑震荡（也被称为轻度创伤性脑损伤- mTBI）不仅是儿童在车祸中遭受的最常见的伤害，而且往往导致影响儿童生活质量的不良后果。了解儿童mTBI的生物力学不仅可以预防汽车损伤，还可以推进CChIPS扩展到运动损伤预防的战略目标。这项基础研究提案解决了行业对数据的需求，以推动预防儿童mTBI的安全创新。本研究的主要目标是：1)验证基于头盔的传感器测量戴头盔的青少年冰球运动员头部加速度的能力；2)量化青少年冰球运动员在一个典型赛季中所经历的头部生物力学，并将这些与测量的神经认知缺陷联系起来。通过深入了解与医学数据相关的脑震荡损伤机制和损伤指标，本研究将导致新的ATD（人体测量测试装置）、损伤标准和测试方案。这些新工具将推动汽车和运动器材行业预防儿童mTBI的技术产品开发周期。提出的工作将提供与青春期前头部撞击相关的神经和认知结果的工程指标相关的新数据。该项目还促进了在瑞典建立CChIPS国际网站，并为吸引来自运动损伤预防行业的新成员提供了一个平台。