DISSERTATION RESEARCH: Understanding the evolutionary consequences of sociality through comparative and genome-wide analyses of social and solitary rodents
论文研究:通过对群居和独居啮齿动物进行比较和全基因组分析,了解社会性的进化后果
基本信息
- 批准号:1309436
- 负责人:
- 金额:$ 2.03万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:2013
- 资助国家:美国
- 起止时间:2013-07-01 至 2016-06-30
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Whether an animal lives alone or with others has important implications for numerous aspects of an organism's biology. Social interactions and group living are integral aspects of some of the most exciting and intensely studied topics in behavioral biology, from the field of human psychopathology to investigations of cooperative behavior and reproductive suppression in animal societies. Understanding exactly how and why sociality evolves as an alternative to the more common trait of solitary living observed in many animals has become a topic of particular interest because growing evidence suggests that group living can incur a number of costs; for instance, animals that live in large social groups often experience an increased risk of exposure to parasites and communicable diseases compared to solitary species. This project endeavors to elucidate the ways in which social animals cope with the unique pressures associated with group living, particularly with regards to immune function, by comparing the variation in immune genes of closely related and ecologically similar species that differ in their social organization. To do this, the project uses newly developed, highly efficient laboratory procedures that allow sequencing of all active genes at the same time, thereby providing a very complete picture of immunogenetic variation. Characterizing the differences in immune genes between social and solitary species will provide insights into which genes are potentially responsible for allowing social animals - including humans - to cope with increased pathogen pressures as well as a further understanding of how disease resistance evolves and is maintained. Thus, by investigating the behavioral correlates of variation in genes found in all mammals, this work will inform current understanding of the mammalian immune system in general. This research will also provide opportunities for undergraduate involvement in research and training in both biology and bioinformatics
动物是单独生活还是与其他动物一起生活,对生物体生物学的许多方面都有重要影响。社会互动和群体生活是行为生物学中一些最令人兴奋和深入研究的主题的组成部分,从人类精神病理学领域到动物社会中合作行为和生殖抑制的调查。确切地理解社会性如何以及为什么进化为许多动物中观察到的更常见的独居特征的替代品,已经成为一个特别感兴趣的话题,因为越来越多的证据表明,群体生活可能会产生一些成本;例如,生活在大型社会群体中的动物与独居物种相比,接触寄生虫和传染病的风险往往会增加。本项目旨在通过比较密切相关和生态相似的物种在社会组织方面的差异,阐明社会动物科普与群体生活相关的独特压力的方式,特别是关于免疫功能。为此,该项目使用新开发的高效实验室程序,允许同时对所有活性基因进行测序,从而提供免疫遗传变异的非常完整的图片。描述社会和孤独物种之间免疫基因的差异将提供洞察哪些基因可能负责允许社会动物-包括人类-科普增加的病原体压力,以及进一步了解抗病性如何进化和维持。因此,通过研究在所有哺乳动物中发现的基因变异的行为相关性,这项工作将为目前对哺乳动物免疫系统的一般理解提供信息。这项研究还将为本科生提供参与生物学和生物信息学研究和培训的机会
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Eileen Lacey其他文献
Eileen Lacey的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Eileen Lacey', 18)}}的其他基金
DISSERTATION RESEARCH: The dynamics of socio-chemo cues across a contact zone in the California vole (Microtus californicus)
论文研究:加州田鼠(Microtus californicus)接触区的社会化学线索的动态
- 批准号:
1701750 - 财政年份:2017
- 资助金额:
$ 2.03万 - 项目类别:
Standard Grant
DISSERTATION RESEARCH: Immunogene Mediated Mate Choice in Populations of Peromyscus spp. Rodents with Different Mating Systems
论文研究:白鼠属种群中免疫基因介导的配偶选择。
- 批准号:
1502063 - 财政年份:2015
- 资助金额:
$ 2.03万 - 项目类别:
Standard Grant
DISSERTATION RESEARCH: Individual Responses to Environmental Change: Contrasting the Behavior and Physiology of two Chipmunk Species
论文研究:个体对环境变化的反应:比较两种花栗鼠的行为和生理学
- 批准号:
1406997 - 财政年份:2014
- 资助金额:
$ 2.03万 - 项目类别:
Standard Grant
COLLABORATIVE RESEARCH: RAPID: Effects of Volcanic Activity on Demographic and Genetic Structure in Tuco-Tucos
合作研究:RAPID:火山活动对图科-图科斯人口和遗传结构的影响
- 批准号:
1201541 - 财政年份:2011
- 资助金额:
$ 2.03万 - 项目类别:
Standard Grant
DISSERTATION RESEARCH: MHC and Mating Systems: Is sexual behavior related to selection on MHC genes?
论文研究:MHC 和交配系统:性行为与 MHC 基因选择有关吗?
- 批准号:
0909798 - 财政年份:2009
- 资助金额:
$ 2.03万 - 项目类别:
Standard Grant
Collaborative Research: A Climate Station Network for the UC Natural Reserve System
合作研究:加州大学自然保护区系统气候站网络
- 批准号:
0936032 - 财政年份:2009
- 资助金额:
$ 2.03万 - 项目类别:
Standard Grant
Dissertation Research: Adaptive Significance of Male Parental Care in Tamarins (Saguinus geoffroyi)
论文研究:狨猴雄性育儿抚育的适应性意义(Saguinus geoffroyi)
- 批准号:
0608467 - 财政年份:2006
- 资助金额:
$ 2.03万 - 项目类别:
Standard Grant
Patterns and Processes of Genetic Diversification in Solitary and Social Subterranean Rodents
独居和群居地下啮齿动物遗传多样性的模式和过程
- 批准号:
0128857 - 财政年份:2002
- 资助金额:
$ 2.03万 - 项目类别:
Standard Grant
DISSERTATION RESEARCH: Cooperative Display Behavior in the Lance-Tailed Manakin
论文研究:矛尾侏儒鸟的合作展示行为
- 批准号:
0104961 - 财政年份:2001
- 资助金额:
$ 2.03万 - 项目类别:
Standard Grant
RPG: Social Behavior And Population Genetics of Subterranean Rodents
RPG:地下啮齿动物的社会行为和种群遗传学
- 批准号:
9704462 - 财政年份:1997
- 资助金额:
$ 2.03万 - 项目类别:
Standard Grant
相似国自然基金
Research on Quantum Field Theory without a Lagrangian Description
- 批准号:24ZR1403900
- 批准年份:2024
- 资助金额:0.0 万元
- 项目类别:省市级项目
Cell Research
- 批准号:31224802
- 批准年份:2012
- 资助金额:24.0 万元
- 项目类别:专项基金项目
Cell Research
- 批准号:31024804
- 批准年份:2010
- 资助金额:24.0 万元
- 项目类别:专项基金项目
Cell Research (细胞研究)
- 批准号:30824808
- 批准年份:2008
- 资助金额:24.0 万元
- 项目类别:专项基金项目
Research on the Rapid Growth Mechanism of KDP Crystal
- 批准号:10774081
- 批准年份:2007
- 资助金额:45.0 万元
- 项目类别:面上项目
相似海外基金
Doctoral Dissertation Research: Innovating Iconographic Analysis to Improve Understanding of the Relationship between Social Organization and Ritual in Indigenous American Culture
博士论文研究:创新图像分析以增进对美国原住民文化中社会组织与仪式之间关系的理解
- 批准号:
2320213 - 财政年份:2023
- 资助金额:
$ 2.03万 - 项目类别:
Standard Grant
Doctoral Dissertation Research: Understanding how minority dialect-speaking children use inflectional verb morphology in sentence processing and word learning.
博士论文研究:了解少数民族方言儿童如何在句子处理和单词学习中使用屈折动词形态。
- 批准号:
2234811 - 财政年份:2023
- 资助金额:
$ 2.03万 - 项目类别:
Standard Grant
Doctoral Dissertation Research: Understanding possibilities in children's counterfactual reasoning
博士论文研究:理解儿童反事实推理的可能性
- 批准号:
2234592 - 财政年份:2023
- 资助金额:
$ 2.03万 - 项目类别:
Standard Grant
Doctoral Dissertation Research in DRMS: Understanding the Perceptions of Urban Residents in the U.S. Gulf Coast Region towards Green Infrastructure
DRMS 博士论文研究:了解美国墨西哥湾沿岸地区城市居民对绿色基础设施的看法
- 批准号:
2117222 - 财政年份:2021
- 资助金额:
$ 2.03万 - 项目类别:
Standard Grant
Doctoral Dissertation Research in DRMS: Understanding the American Publics COVID-19 Vaccination Uptake
DRMS 博士论文研究:了解美国公众 COVID-19 疫苗接种情况
- 批准号:
2117257 - 财政年份:2021
- 资助金额:
$ 2.03万 - 项目类别:
Standard Grant
Doctoral Dissertation Research: Understanding the Role of Boundary Spanners in Arctic Co-production of Knowledge Research
博士论文研究:了解边界扳手在北极知识研究共同生产中的作用
- 批准号:
2134867 - 财政年份:2021
- 资助金额:
$ 2.03万 - 项目类别:
Standard Grant
Doctoral Dissertation Research: Understanding Resettlement of Communities
博士论文研究:理解社区安置
- 批准号:
2034814 - 财政年份:2021
- 资助金额:
$ 2.03万 - 项目类别:
Standard Grant
Doctoral Dissertation Research in DRMS: Building a comprehensive understanding of enterprise risks and their interdependencies for improved risk-intelligence
DRMS 博士论文研究:全面了解企业风险及其相互依赖性,以提高风险情报
- 批准号:
2049782 - 财政年份:2021
- 资助金额:
$ 2.03万 - 项目类别:
Standard Grant
Doctoral Dissertation Research: Understanding the Barriers to Political Representation of Women
博士论文研究:了解妇女政治代表权的障碍
- 批准号:
1841080 - 财政年份:2020
- 资助金额:
$ 2.03万 - 项目类别:
Standard Grant
Doctoral Dissertation Research in DRMS: El Poder de la Familia: Understanding the role of familism on Latino environmentalism
DRMS 博士论文研究:El Poder de la Familia:理解家庭主义对拉丁裔环保主义的作用
- 批准号:
2018051 - 财政年份:2020
- 资助金额:
$ 2.03万 - 项目类别:
Standard Grant