DISSERTATION RESEARCH: Elucidating Evolutionary Histories of Multiple Chipmunk Parasites Using Next Generation Sequencing
论文研究:利用下一代测序阐明多种花栗鼠寄生虫的进化史
基本信息
- 批准号:1311076
- 负责人:
- 金额:$ 1.96万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:2013
- 资助国家:美国
- 起止时间:2013-07-01 至 2015-06-30
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
This research investigates the response of parasites to the diversification of their chipmunk hosts across temporally and spatially variable environments in western North America. Chipmunks are frequently infected with externally-parasitic sucking lice and internally-parasitic pinworms. It is unclear if parasite lineages are restricted to individual chipmunk species and diversifying in tandem with the host lineages (codiversification), or if they are adapted to a resource shared among chipmunks and thus can infect any species of chipmunk they encounter. This project tests for codiversification among each parasite and the hosts and investigates the role of climate in determining parasite distribution and diversity. The research uses a combination of geographic mapping and genetic sequencing techniques to determine the influence of climate, geography, and species associations in evolutionary diversification.An integrated view of the evolutionary history of hosts and parasites has wide-ranging implications, including consequences of climate change on pathogens and parasites. Beyond the current interest in biotic responses to climate change, studying host-parasite associations allows for testing of foundational coevolutionary rules and hypotheses. This research will provide training for undergraduate and graduate students in field, museum, and molecular lab research. Additionally, this project will feed into an effort to integrate museum specimens and databases into undergraduate courses through inquiry-driven student projects that raise awareness of the value of natural history collections. Through this research, students will be introduced to cutting-edge analytical and collaborative approaches in bioinformatics. Chipmunks are familiar, highly visible, and provide a gateway to conversations with school groups, the public, and others about conservation, evolution, and parasites.
本研究调查了寄生虫的响应,其花栗鼠宿主的多样化在北美西部的时间和空间变化的环境。花栗鼠经常感染外部寄生的吸虱和内部寄生的蛲虫。目前尚不清楚寄生虫谱系是否仅限于单个花栗鼠物种,并与宿主谱系一起多样化(共同多样化),或者它们是否适应花栗鼠之间共享的资源,从而可以感染它们遇到的任何花栗鼠物种。该项目测试每种寄生虫和宿主之间的共同多样化,并调查气候在确定寄生虫分布和多样性方面的作用。该研究使用地理绘图和基因测序技术相结合,以确定气候,地理和物种协会在进化多样化的影响。宿主和寄生虫进化历史的综合观点具有广泛的影响,包括气候变化对病原体和寄生虫的后果。除了目前对生物对气候变化的反应的兴趣之外,研究宿主-寄生虫协会还可以测试基本的共同进化规则和假设。这项研究将为本科生和研究生提供野外、博物馆和分子实验室研究方面的培训。此外,该项目将通过调查驱动的学生项目,提高对自然历史收藏品价值的认识,努力将博物馆标本和数据库整合到本科课程中。通过这项研究,学生将被介绍到生物信息学的尖端分析和协作方法。花栗鼠是熟悉的,高度可见的,并提供了一个与学校团体,公众和其他有关保护,进化和寄生虫的对话的门户。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Joseph Cook其他文献
Linkages among physical, biogeochemical and biological oceanography: some examples and strategies
物理、生物地球化学和生物海洋学之间的联系:一些例子和策略
- DOI:
- 发表时间:
2020 - 期刊:
- 影响因子:0
- 作者:
Piotr Rozwalak;Pawel Podkowa;Jakub Buda;Przemyslaw Niedzielski;Szymon Kawecki;Roberto Ambrosini;Roberto S. Azzoni;Giovanni Baccolo;Jorge L. Ceballos;Joseph Cook;Nozomu Takeuchi 他(全33名);伊島翔大,関根みくり,藤江真也;Shoshiro Minobe - 通讯作者:
Shoshiro Minobe
Valuing Changes in Time Use in Low- and Middle-Income Countries
重视低收入和中等收入国家时间利用的变化
- DOI:
10.1017/bca.2018.21 - 发表时间:
2018 - 期刊:
- 影响因子:3.4
- 作者:
D. Whittington;Joseph Cook - 通讯作者:
Joseph Cook
The Effects of Eligibility and Voluntary Participation on the Distribution of Benefits in Environmental Programs: An Application to Green Stormwater Infrastructure
资格和自愿参与对环境项目利益分配的影响:在绿色雨水基础设施中的应用
- DOI:
- 发表时间:
2022 - 期刊:
- 影响因子:1.4
- 作者:
Daniel A. Brent;Joseph Cook;Allison Lassiter - 通讯作者:
Allison Lassiter
Desalination membranes based on directly sulfonated poly(arylene ether sulfone) copolymers
基于直接磺化聚(亚芳基醚砜)共聚物的脱盐膜
- DOI:
- 发表时间:
2008 - 期刊:
- 影响因子:0
- 作者:
H. Park;W. Xie;Joseph Cook;J. Mcgrath;B. Freeman - 通讯作者:
B. Freeman
Confusion in Risk Aversion Experiments in Low-Income Countries
低收入国家风险规避实验的混乱
- DOI:
10.2139/ssrn.2617701 - 发表时间:
2015 - 期刊:
- 影响因子:0
- 作者:
Joseph Cook - 通讯作者:
Joseph Cook
Joseph Cook的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Joseph Cook', 18)}}的其他基金
Collaborative Research: PurSUiT: Systematic viral discovery through structured search of host phylogeny
合作研究:PurSUiT:通过宿主系统发育的结构化搜索系统性病毒发现
- 批准号:
2302678 - 财政年份:2023
- 资助金额:
$ 1.96万 - 项目类别:
Standard Grant
Collaborative Research: Ranges: Building Capacity to Extend Mammal Specimens from Western North America
合作研究:范围:建设能力以扩展北美西部的哺乳动物标本
- 批准号:
2228387 - 财政年份:2023
- 资助金额:
$ 1.96万 - 项目类别:
Continuing Grant
PIPP Phase I: Center for Emerging Pathogen Prediction and Integration
PIPP 第一阶段:新兴病原体预测和整合中心
- 批准号:
2155222 - 财政年份:2022
- 资助金额:
$ 1.96万 - 项目类别:
Standard Grant
Collaborative Research: STEPP-NET: Steppe Parasite Networks
合作研究:STEPP-NET:草原寄生虫网络
- 批准号:
2120469 - 财政年份:2021
- 资助金额:
$ 1.96万 - 项目类别:
Standard Grant
EAGER: Temporal Occurrence, Spatial Dynamics, and Host Diversity of Betacoronaviruses, including SARS-CoV-2, with Implications for Mitigating Covid-19 Re-emergence
EAGER:包括 SARS-CoV-2 在内的 β 冠状病毒的时间发生、空间动态和宿主多样性,对缓解 Covid-19 重新出现的影响
- 批准号:
2033482 - 财政年份:2020
- 资助金额:
$ 1.96万 - 项目类别:
Standard Grant
Collaborative Research: Digitization TCN: Digitizing Collections to Trace Parasite-Host Associations and Predict the Spread of Vector-borne Disease
合作研究:数字化 TCN:数字化馆藏以追踪寄生虫-宿主关联并预测媒介传播疾病的传播
- 批准号:
1901920 - 财政年份:2019
- 资助金额:
$ 1.96万 - 项目类别:
Standard Grant
PRFB Workshop- Research Using Biological Collections; November 7-9, 2017; Harvard University
PRFB 研讨会 - 使用生物收藏品进行研究;
- 批准号:
1746177 - 财政年份:2017
- 资助金额:
$ 1.96万 - 项目类别:
Standard Grant
CSBR:Natural History: Upgrade and transfer of the Museum of Southwestern Biologys Division of Genomic Resources frozen tissue collection to Nitrogen vapor storage.
CSBR:自然历史:将西南生物博物馆基因组资源部冷冻组织收藏升级并转移到氮蒸气储存。
- 批准号:
1561342 - 财政年份:2016
- 资助金额:
$ 1.96万 - 项目类别:
Continuing Grant
Collaborative Research: Integrated Inventory of Biomes of the Arctic
合作研究:北极生物群落综合清查
- 批准号:
1258010 - 财政年份:2013
- 资助金额:
$ 1.96万 - 项目类别:
Continuing Grant
Integration and Curation of the Robert and Virginia Rausch Helminthological Collection- A Resource for Science and Society in the MSB Division of Parasitology
Robert 和 Virginia Rausch 蠕虫学收藏的整合和管理 - MSB 寄生虫学部门的科学和社会资源
- 批准号:
1057383 - 财政年份:2011
- 资助金额:
$ 1.96万 - 项目类别:
Continuing Grant
相似国自然基金
Research on Quantum Field Theory without a Lagrangian Description
- 批准号:24ZR1403900
- 批准年份:2024
- 资助金额:0.0 万元
- 项目类别:省市级项目
Cell Research
- 批准号:31224802
- 批准年份:2012
- 资助金额:24.0 万元
- 项目类别:专项基金项目
Cell Research
- 批准号:31024804
- 批准年份:2010
- 资助金额:24.0 万元
- 项目类别:专项基金项目
Cell Research (细胞研究)
- 批准号:30824808
- 批准年份:2008
- 资助金额:24.0 万元
- 项目类别:专项基金项目
Research on the Rapid Growth Mechanism of KDP Crystal
- 批准号:10774081
- 批准年份:2007
- 资助金额:45.0 万元
- 项目类别:面上项目
相似海外基金
Collaborative Research: Elucidating High Temperature Deformation Mechanisms in Refractory Multi-Principal-Element Alloys
合作研究:阐明难熔多主元合金的高温变形机制
- 批准号:
2313860 - 财政年份:2023
- 资助金额:
$ 1.96万 - 项目类别:
Standard Grant
Collaborative Research: RUI: Elucidating Design Rules for non-NRPS Incorporation of Amino Acids on Polyketide Scaffolds
合作研究:RUI:阐明聚酮化合物支架上非 NRPS 氨基酸掺入的设计规则
- 批准号:
2300890 - 财政年份:2023
- 资助金额:
$ 1.96万 - 项目类别:
Continuing Grant
Collaborative Research: RUI: Elucidating Design Rules for non-NRPS Incorporation of Amino Acids on Polyketide Scaffolds
合作研究:RUI:阐明聚酮化合物支架上非 NRPS 氨基酸掺入的设计规则
- 批准号:
2300891 - 财政年份:2023
- 资助金额:
$ 1.96万 - 项目类别:
Continuing Grant
Collaborative Research: MRA: Elucidating the multi-dimensionality and scaling of avian diversity-vegetation relationships
合作研究:MRA:阐明鸟类多样性与植被关系的多维性和尺度
- 批准号:
2307188 - 财政年份:2023
- 资助金额:
$ 1.96万 - 项目类别:
Standard Grant
Elucidating How the Contributions of Basic Scientific Research in Reproductive Biology Cultivate the Development of Medical Students' Perspectives on Life and Death
阐明生殖生物学基础科学研究的贡献如何培养医学生生死观的发展
- 批准号:
23K17579 - 财政年份:2023
- 资助金额:
$ 1.96万 - 项目类别:
Grant-in-Aid for Challenging Research (Exploratory)
Basic Research for Elucidating and Overcoming the Mechanisms of Progression of Early-Stage Lung Adenocarcinoma
阐明和克服早期肺腺癌进展机制的基础研究
- 批准号:
23KK0155 - 财政年份:2023
- 资助金额:
$ 1.96万 - 项目类别:
Fund for the Promotion of Joint International Research (International Collaborative Research)
Collaborative Research: Elucidating the Role of Natural Aerosols in Modulating Boundary Layer Clouds and Precipitation in the Southern Ocean
合作研究:阐明天然气溶胶在调节南大洋边界层云和降水中的作用
- 批准号:
2246489 - 财政年份:2023
- 资助金额:
$ 1.96万 - 项目类别:
Continuing Grant
Collaborative Research: Elucidating High Temperature Deformation Mechanisms in Refractory Multi-Principal-Element Alloys
合作研究:阐明难熔多主元合金的高温变形机制
- 批准号:
2313861 - 财政年份:2023
- 资助金额:
$ 1.96万 - 项目类别:
Standard Grant
Collaborative Research: Elucidating the roles of biogenic exudates in the cycling and uptake of rare earth elements
合作研究:阐明生物渗出物在稀土元素循环和吸收中的作用
- 批准号:
2221913 - 财政年份:2023
- 资助金额:
$ 1.96万 - 项目类别:
Standard Grant
Collaborative Research: Elucidating the Ocean Dynamics Governing Melt at Glaciers Using Lagrangian Floats
合作研究:利用拉格朗日浮标阐明控制冰川融化的海洋动力学
- 批准号:
2319494 - 财政年份:2023
- 资助金额:
$ 1.96万 - 项目类别:
Standard Grant