Public and Proprietary Knowledge in Biotechnology: An Historical and Sociological Analysis of First Generation Recombinant DNA Pharmaceuticals Development

20世纪80年代的“生物技术革命”是目前大学生命科学与商业之间联系模式的形成时期。因此，在最近这一关键事件中，对公共科学知识和专有科学知识之间不断变化的边界进行更清晰的分析，将为当今大学科学的社会角色提供宝贵的见解。除了科学政策和社会学问题外，这种对第一批生物技术公司的科学倡议、商业战略以及与大学关系的更准确描述，也可能有助于为旨在促进生命科学领域成功的商业学术做出贡献。

The 'biotechnology revolution' of the 1980s was a formative period that set the present pattern of links between university life science and commerce. A clearer analysis of the shifting boundary between public and proprietary scientific knowledge in this key recent episode will thus provide valuable insight into the social role of university-based science today. In addition to matters of science policy and sociology, this more accurate account of the scientific initiatives, commercial strategies, and relationships with universities among the first biotechnology firms may also contribute to business scholarship aiming to foster success in the life science sector.