MRI: Acquisition of a Dionex Accelerated Solvent Extractor for Biogeochemistry, Toxicology, and Marine Science Research at Hawaii Pacific University

该奖项用于购买Dionex加速溶剂提取(ASE)系统，以增加教职员工和学生的研究机会，并改善HPU的教学基础设施。ASE系统将用于由NSF和其他机构资助的各种活跃的研究项目，这些项目需要频繁使用ASE设备来提取脂质、环境污染物和天然代谢产品。该仪器将用于若干不同的项目，包括：(A)从西北太平洋深埋的Shimokita煤层(海底以下1498.48米和2406.84米)分离出的嗜压细菌在脂肪生物合成过程中的碳同位素分馏；(B)评估Kawainui沼泽生态系统的历史变化；(C)测量野生海豚体内应激诱导的激素，作为对环境不利影响的指标；(D)建立天然产品化学库；(E)测量海洋脊椎动物组织中的有机污染物。HPU目前正从一所以本科为主、非博士授课的教学机构转型为一所拥有强大研究项目的综合性大学，这种最先进的仪器将有助于促进这一转型。博士后研究助理和硕士研究生和本科生将接受使用该仪器的培训。夏威夷太平洋大学(HPU)是瓦胡岛上一所少数族裔服务的本科生研究机构，与美国大陆相比，该州几乎没有高等教育中心。HPU的学生群体中有相当一部分是当地的夏威夷原住民以及来夏威夷接受大学教育的太平洋岛民。因此，该仪器的资助将对生物、生物化学、海洋生物学和海洋学等领域的不同学生群体的研究和教育产生广泛影响。

This award funds the acquisition of a Dionex Accelerated Solvent Extraction (ASE) system to enhance faculty and student research opportunities and to improve teaching infrastructure at HPU. The ASE system will be used in a variety of active research projects funded by NSF and other agencies which require frequent use of ASE equipment for extraction of lipids, environmental contaminants, and natural metabolic products. The instrument will be used for a number of diverse projects including (a) carbon isotope fractionation in lipid biosynthesis by piezophilic bacteria isolated from the deeply buried Shimokita Coalbed (1498.48 and 2406.84 meter below the seafloor) in the northwest Pacific; (b) assessing historical changes in Kawai`nui marsh ecosystem; (c) measuring stress-induced hormones in wild dolphins as an indicator of negative environmental impacts on dolphin populations (d) the development of natural product chemical libraries; and (e) measuring organic contaminants in tissues of marine vertebrates. HPU is currently in transition from a predominantly undergraduate, non-Ph.D. granting teaching institution into a comprehensive university with a strong research program, and such state-of-the-art instrumentation will help facilitate this transition. Postdoctoral research associates and M.S. graduate and undergraduate students will be trained on the use of the instrument. Hawaii Pacific University (HPU) is a minority serving undergraduate research institution on the Island of Oahu in a state with few centers of higher learning in Hawaii compared with the continental United States. The HPU student population includes significant representation by local native Hawaiians as well as Pacific Islanders that come to Hawaii for a college education. Hence the funding of this instrumentation will have broad impacts on a diverse student population in research and education in fields such as Biology, Biochemistry, Marine Biology and Oceanography.