RAPID: Collaborative Research: Fate and Transport of Antibiotics and Antibiotic Resistance Genes During Historic Colorado Flood

RAPID：合作研究：历史性科罗拉多洪水期间抗生素和抗生素抗性基因的命运和运输

• 批准号: 1402346
• 负责人: Mazdak Arabi
• 金额: $ 1.4万
• 依托单位: Colorado State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-12-15 至 2015-11-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1402346&HistoricalAwards=false
• 关键词: RAPID; Collaborative; Research; Fate; Transport

1402346MazdakRecently it has come to the attention of the scientific community and to the public that pharmaceutical compounds are being found in many natural waters, for example, streams, rivers, lakes and sometimes groundwater. The U.S. Centers for Disease Control and Prevention, the World Health Organization, and numerous other global and national agencies have recognized that one potential implication of these findings is that bacterial normally found in natural water may develop resistance to the antibiotics. This may be one of the most critical challenges of this century. Studies have shown that antibiotic resistant bacteria can be selected, maintained, and transported within various environmental compartments, by environmental compartments we mean streams and rivers. This project seeks to explore the impact of the recent flooding in Colorado on what is referred to as mobilization of pharmaceuticals (the partitioning of pharmaceutical compounds from sediments to the flowing water) and to investigate whether or not there is an increase in antibiotic resistance in these organisms associated with these waters. With a database of 10 years in the South Platte River the research team is well positioned to conduct additional sampling. This project will be supporting graduate and undergraduate students from three participating universities and will be used for the students as part of undergraduate independent research or graduate student thesis and dissertations.

1402346 Mazdakrecelyly从科学界和公众引起了人们的注意，例如在许多天然水域中都发现了药物化合物，例如，溪流，河流，湖泊，有时是地下水。 美国疾病控制和预防，世界卫生组织以及许多其他全球和国家机构都认识到，这些发现的潜在含义是通常在天然水中发现的细菌可能会产生对抗生素的耐药性。 这可能是本世纪最关键的挑战之一。 研究表明，可以通过环境区室在各种环境室内选择，维护和运输抗生素抗生素，这是指我们的溪流和河流。 该项目旨在探索科罗拉多州最近的洪水对动员药物的影响（将药物化合物从沉积物到流动水的分配），并研究与这些生物有关的抗生素耐药性是否有所增加。 在南普拉特河（South Platte River）的数据库中，研究小组有能力进行额外的抽样。 该项目将支持来自三所参与大学的研究生和本科生，并将用于学生，作为本科独立研究或研究生论文和论文的一部分。