MRI: Acquisition of a Scanning Electron Microscope (SEM) for Performing Multidisciplinary Research at Delaware State University Imaging Facility

MRI：购买扫描电子显微镜 (SEM)，用于特拉华州立大学成像设施进行多学科研究

• 批准号: 1427089
• 负责人: Mukti Rana
• 金额: $ 50.11万
• 依托单位: Delaware State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-08-15 至 2017-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1427089&HistoricalAwards=false
• 关键词: MRI; Acquisition; Scanning; Electron; Microscope

Non-technical: This Major Research Instrumentation (MRI) grant awarded to Delaware State University (DSU) provides funding for the acquisition of a Scanning Electron Microscope (SEM). This high-resolution imaging microscope enhances the research and educational capabilities at DSU, a historically-black university with a large pool of talented students who have been traditionally underrepresented in the fields of Science, Technology, Engineering, and Mathematics (STEM). Thanks to this acquisition, DSU STEM students get "hands on" experience and training in this broadly-used technology. Further, the SEM is an impetus to stimulate new opportunities, and to develop new collaborative projects among DSU and non-DSU researchers. Most particularly, it strengthens the mission of the NSF-funded Center for Research Excellence in Science and Technology at DSU: the Optical Science Center for Applied Research.Technical: The goals of this MRI project are: (1) to develop and design novel materials for integrated circuits and their applications, (2) to assess the efficiency of (Deoxyribonucleic acid) DNA delivery systems, (3) to understand the estrogen receptors in goldfish, and (4) to characterize and probe the nanoscopic structures of diverse biopolymers. In addition, the instrument provides other capabilities such as energy dispersive X-ray spectroscopy microanalysis system, which can be used to determine the elemental composition of a specimen. Thus, the instrument contributes to the successful realization of various ongoing research projects at DSU, including: i) the fabrication of a nanofiber in situ electroporation chip to deliver DNA into cells, ii) the study of membrane-associated estrogen receptors in the Mauthner cell circuit of goldfish, and iii) the characterization of tubulin nanorings.

非技术性：授予特拉华州州立大学（DSU）的主要研究仪器（MRI）补助金为扫描电子显微镜（SEM）的收购提供资金。这款高分辨率成像显微镜增强了DSU的研究和教育能力，DSU是一所历史悠久的黑人大学，拥有大量有才华的学生，他们在科学，技术，工程和数学（STEM）领域的传统代表性不足。 由于此次收购，DSU STEM学生获得了这种广泛使用的技术的“动手”经验和培训。此外，SEM是一种动力，以刺激新的机会，并开发新的合作项目之间的DSU和非DSU的研究人员。 最重要的是，它加强了NSF资助的DSU科学技术卓越研究中心的使命：应用研究光学科学中心。技术：该MRI项目的目标是：（1）开发和设计用于集成电路及其应用的新材料，（2）评估（脱氧核糖核酸）DNA传递系统，（3）了解金鱼中的雌激素受体，（4）表征和探测各种生物聚合物的纳米级结构。此外，该仪器还提供其他功能，如能量色散X射线光谱微量分析系统，可用于确定样品的元素组成。 因此，该仪器有助于DSU各种正在进行的研究项目的成功实现，包括：i）制造一种原位电穿孔芯片，将DNA传递到细胞中，ii）研究金鱼Mauthner细胞回路中的膜相关雌激素受体，iii）微管蛋白纳米环的表征。