MRI: Acquisition of a Multiwavelength Raman Spectroscopy Facility for Catalysis, Biological, Nanoscale and Materials Research

从主要研究仪器（MRI）计划的这一奖项和化学研究仪器（CRIF）计划的支持下，教授迈克尔Neidig和合作者从罗切斯特大学将获得一个多波长拉曼光谱仪周围的三重光谱仪与多个激光线，允许从近红外近紫外区域的拉曼数据的收集。 该区域中的拉曼光谱用于测量材料的振动频率。这提供了关于物质的化学组成和结构的信息。它是一种广泛使用的工具，用于了解化学和生物系统的特性以及材料研究。该仪器将是一个多用户设施开放给用户在大学和罗切斯特地区，包括教师在圣约翰费舍尔学院和纽约州立大学Geneseo。它将促进学生在各级的研究和课程工作的培训。 该奖项旨在加强各级的研究和教育，特别是在以下领域：（a）研究有机合成中非贵金属催化的结构、键合和机制;（B）进行飞秒受激拉曼光谱探测的超快光化学;（c）在细胞和组织一级分析生物标本;（d）研究血红素蛋白和用于能量转换的工程化金属蛋白中的第二球效应;（e）分析复合处方;（f）阐明A-β肽在金纳米胶体上的结合构象;以及（g）研究用于活细胞中基因递送的中空微针。

With this award from the Major Research Instrumentation (MRI)program and support from the Chemistry Research Instrumentation (CRIF) program, Professor Michael Neidig and collaborators from the University of Rochester will acquire a multiwavelength Raman spectrometer built around a triple spectrometer with multiple laser lines to allow collection of Raman data from the near-IR to near-UV regions. Raman spectroscopy in this region is used to measure the vibrational frequencies of a material. This provides information on the chemical composition and structure of substances. It is a widely used tool to understand the properties of chemical and biological systems and in materials research. The instrument will be a multi-user facility open to users at the university and in the Rochester area including faculty at St. John Fisher College and SUNY-Geneseo. It will advance the training of students in their research and course work at all levels. The award is aimed at enhancing research and education at all levels, especially in areas such as (a) investigating structure, bonding and mechanism in non-precious metal catalysis for organic syntheses; (b) carrying out ultrafast photochemistry probed by femtosecond stimulated Raman spectroscopy; (c) analyzing biological specimens at the cell and tissue level; (d) studying second-sphere effects in heme proteins and engineered metalloproteins for energy conversion; (e) analyzing compounded prescriptions; (f) elucidating binding conformation of A-beta peptides over gold nanocolloids; and (g) studying hollow microneedles for gene delivery in living cells.