MRI: Acquisition of a Multiwavelength Raman Spectroscopy Facility for Catalysis, Biological, Nanoscale and Materials Research

MRI：购置用于催化、生物、纳米尺度和材料研究的多波长拉曼光谱设备

• 批准号: 1427882
• 负责人: Michael Neidig
• 金额: $ 25.02万
• 依托单位: University of Rochester
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-08-01 至 2016-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1427882&HistoricalAwards=false
• 关键词: MRI; Acquisition; Multiwavelength; Raman; Spectroscopy

With this award from the Major Research Instrumentation (MRI)program and support from the Chemistry Research Instrumentation (CRIF) program, Professor Michael Neidig and collaborators from the University of Rochester will acquire a multiwavelength Raman spectrometer built around a triple spectrometer with multiple laser lines to allow collection of Raman data from the near-IR to near-UV regions. Raman spectroscopy in this region is used to measure the vibrational frequencies of a material. This provides information on the chemical composition and structure of substances. It is a widely used tool to understand the properties of chemical and biological systems and in materials research. The instrument will be a multi-user facility open to users at the university and in the Rochester area including faculty at St. John Fisher College and SUNY-Geneseo. It will advance the training of students in their research and course work at all levels. The award is aimed at enhancing research and education at all levels, especially in areas such as (a) investigating structure, bonding and mechanism in non-precious metal catalysis for organic syntheses; (b) carrying out ultrafast photochemistry probed by femtosecond stimulated Raman spectroscopy; (c) analyzing biological specimens at the cell and tissue level; (d) studying second-sphere effects in heme proteins and engineered metalloproteins for energy conversion; (e) analyzing compounded prescriptions; (f) elucidating binding conformation of A-beta peptides over gold nanocolloids; and (g) studying hollow microneedles for gene delivery in living cells.

凭借重大研究仪器 (MRI) 项目的奖项以及化学研究仪器 (CRIF) 项目的支持，罗切斯特大学的 Michael Neidig 教授和合作者将获得一台围绕具有多条激光线的三重光谱仪构建的多波长拉曼光谱仪，以收集从近红外到近紫外区域的拉曼数据。 该区域的拉曼光谱用于测量材料的振动频率。这提供了有关物质的化学成分和结构的信息。它是了解化学和生物系统特性以及材料研究中广泛使用的工具。该仪器将是一个多用户设施，向大学和罗切斯特地区的用户开放，包括圣约翰费舍尔学院和纽约州立大学日内西奥分校的教职员工。它将促进学生在各个级别的研究和课程工作方面的培训。 该奖项旨在加强各级的研究和教育，特别是在以下领域：（a）研究有机合成非贵金属催化的结构、键合和机制； (b) 进行飞秒受激拉曼光谱探测的超快光化学； (c) 在细胞和组织水平上分析生物样本； (d) 研究血红素蛋白和工程金属蛋白用于能量转换的第二领域效应； (e) 分析复方处方； (f) 阐明 A-β 肽与金纳米胶体的结合构象； (g) 研究用于活细胞中基因传递的空心微针。